货号：MAB3418B

品牌：Merck Millipore

规格：100UL

目录价：￥6588.00

市场价格：￥5599.80

会员价格：￥5270.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-MAP2 Antibody, clone AP20, Biotin Conjugated | MAB3418B View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: The unconjugated parent antibody (Cat. No. MAB3418) has an observed molecular weight at ~230 kDa. View All» Immunogen: Bovine brain microtubule protein View All» Clone: AP20 View All» Isotype: IgG View All» Background Information: The microtubule-associated protein 2 (MAP-2) is an abundant neuronal cytoskeletal protein that binds to tubulin, stabilizes microtubules (Herzog and Weber, 1978), and is an excellent marker for neurons. MAP-2 is essential for the development and maintenance of neuronal morphology (Matus, 1991). Three primary isoforms of MAP-2, the high molecular weight MAP2a and MAP2b, and the low molecular weight MAP2c (resulting from alternate splicing of the MAP2 gene), have been identified in neurours. (Chung et al., 1996). The low molecular weight isoform, MAP2c, is expressed in developing brain and is down-regulated during brain maturation, whereas the high molecular weight MAP2b is expressed in both developing and adult brain. The MAP2a appears only after brain maturation (Tucker, 1990). All these forms bind to microtubules through a domain near the carboxyl terminus that contains either three or four similar repeats of a 31-amino-acid motif (Lewis et al., 1988). MAP-2 together with MAP-4 and tau proteins belong to the family of thermostable proteins associated with microtubules. View All» Species Reactivity:

• Human

• Mouse

• Rat

• Bovine

• Chicken
  View All» Species Reactivity Note: Demonstrated to react with Rat. Predicted to react with Chicken, Human, and Mouse based on 100% sequence homology. Predicted to react with Bovine based on immunogen design. View All» Application Notes: Immunocytochemistry Analysis: A 1:25 dilution from a representative lot detected MAP2 in rat E18 primary cortex cells. View All» Control: Rat cortex tissue View All» Quality Assurance: Evaluated by Immunohistochemistry in rat cortex tissue.Immunohistochemistry Analysis: A 1:25 dilution of this antibody detected MAP2 in rat cortex tissue. View All» Purification Method: Protein G purified View All» Presentation: Purified mouse monoclonal IgG conjugated to Biotin in PBS with 0.1% sodium azide and 15 mg/mL BSA. View All» Storage Conditions: Maintain refrigerated at 2-8 °C in undiluted aliquots for up to 6 months from date of receipt. View All» UniProt Number: Q0IIA8 View All» Gene Symbol:
  • Map2

  • Mtap2
    View All» Alternate Names:
    • Microtubule-associated protein 2

    • MAP-2

    • MAP2
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Immunocytochemistry View All» Product Name: Anti-MAP2, clone AP20, Biotin Conjugated View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Biotin View All» Host: Mouse View All»
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