Merck Millipore代理MAB3564 Anti-Sodium/Iodine Symporter Antibody, a.a. 625-643, clone FP5A;store at +2℃ to +8℃

2025-06-28

货号:MAB3564

品牌:Merck Millipore

规格:100Ug

目录价:¥4967.00

市场价格:¥4221.95

会员价格:¥3973.60

金山科研平台,产品价格货期咨询微信:jinshanbio Description: Anti-Sodium/Iodine Symporter Antibody, a.a. 625-643, clone FP5A | MAB3564 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Sodium/Iodide Symporter (NIS). The epitope is thought to be in the region of amino acids 625-643 of human NIS. The antibody may show some reactivity to Maltose Binding Protein. View All» Epitope: a.a. 625-643 View All» Immunogen: Maltose Binding Protein fusion protein corresponding to amino acids 468-643 of human NIS (C-terminus). View All» Clone: FP5A View All» Isotype: IgG1κ View All» Species Reactivity: Human View All» Application Notes: Immunoblotting. The antibody recognizes a major band at ~97 kDa and minor bands at 15 kDa, 30 kDa, 68 kDa and 160 kDa. Immunohistochemistry. The antibody works on paraffin embedded tissue sections which have been subjected to antigen retrieval with 10 mM citrate buffer steam for 30 minutes. Optimal working dilutions must be determined by end user. View All» Presentation: Liquid. Buffer = 0.02M Phosphate buffer, 0.25M NaCl with 0.1% sodium azide. View All» Storage Conditions: Maintain at 2-8°C in undiluted aliquots for up to 6 months. View All» UniProt Number: Q92911 View All» Entrez Gene Number: NM_000453.1 View All» Gene Symbol:

  • SLC5A5

  • +I

  • NIS

  • Na

  • -symporter)

  • -cotransporter)

    View All» Alternate Names: Na+/I- Symporter; NIS View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunohistochemistry

    • Immunohistochemistry (Paraffin)

    • Western Blotting

      View All» Entrez Gene Summary: The sodium-iodide symporter (NIS), a member of the sodium/solute symporter family, actively transports iodide across the basolateral plasma membrane of the thyroid follicular cells.[supplied by OMIM] View All» UniProt Summary: FUNCTION: SwissProt: Q92911 # Mediates iodide uptake in the thyroid gland.SIZE: 643 amino acids; 68666 Da SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.TISSUE SPECIFICITY: Expression is primarily in thyroid tissue, but also to a lower extent in mammary gland and ovary. Expression is reduced in tumors.DISEASE: SwissProt: Q92911 # Defects in SLC5A5 are the cause of iodide transport defect (ITD) [MIM:274400]. ITD is characterized by an inability of the thyroid to maintain a concentration difference of readily exchangeable iodine between the plasma and the thyroid gland. It is a cause of congenital hypothyroidism.SIMILARITY: SwissProt: Q92911 ## Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. View All» Brand Family: Chemicon View All» Product Name: Anti-Sodium/Iodine Symporter Antibody, a.a. 625-643, clone FP5A | MAB3564 View All» Concentration: 1 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Purified View All» Host: Mouse View All»

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