货号：MAB3684

品牌：Merck Millipore

规格：100UL

目录价：￥5053.00

市场价格：￥4295.05

会员价格：￥4042.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Cyclin B1 Antibody, clone V152 | MAB3684 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Cyclin B. Cyclin B1 is a marker of cell proliferation and a key component of the cell progression machinery. MAB3684 works well for detecting Cyclin B1 by Western blot and immunohistochemistry. View All» Immunogen: Hamster Cyclin B1. View All» Clone: V152 View All» Isotype: IgG1 View All» Species Reactivity:

• Human

• Mouse
  View All» Application Notes: Western blot Immunohistochemistry (works on paraffin embedded tissue sections) Optimal working dilutions must be determined by the end user. View All» Presentation: Ascites fluid. Liquid. Contains no preservative. View All» Storage Conditions: Maintain at -20°C in undiluted aliquots up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. View All» UniProt Number: P14635 View All» Entrez Gene Number: NM_031966.2 View All» Gene Symbol:
  • CCNB1

  • CCNB
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Western Blotting

    • Immunohistochemistry (Paraffin)
      View All» Entrez Gene Summary: The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. View All» UniProt Summary: FUNCTION: SwissProt: P14635 # Essential for the control of the cell cycle at the G2/M (mitosis) transition.SIZE: 433 amino acids; 48337 Da SUBUNIT: Interacts with the CDC2 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex. Binds HEI10. Interacts with catalytically active RALBP1 and CDC2 during mitosis to form an endocytotic complex during interphase.SUBCELLULAR LOCATION: Cytoplasm. Nucleus. Centrosome.DEVELOPMENTAL STAGE: Accumulates steadily during G2 and is abruptly destroyed at mitosis.PTM: Ubiquitinated by the SCF(NIPA) complex during interphase, leading to its destruction. Not ubiquitinated during G2/M phases.SIMILARITY: SwissProt: P14635 ## Belongs to the cyclin family. Cyclin AB subfamily. View All» Brand Family: Chemicon View All» Product Name: Anti-Cyclin B1 Antibody, clone V152 | MAB3684 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Ascites View All» Host: Mouse View All»
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