货号：04-1074

品牌：Merck Millipore

规格：

目录价：￥4118.00

市场价格：￥3500.30

会员价格：￥3294.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-PECAM-1 [CD31] Antibody, clone EP3095, Rabbit | 04-1074 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes PECAM1. View All» Molecular Weight: 130 kDa View All» Immunogen: Synthetic peptide corresponding to residues on human PECAM-1. View All» Clone: EP3095 View All» Isotype: IgG View All» Background Information: CD31, also known as platelet endothelial cell adhesion molecule 1 (PECAM1) is a type I integral membrane glycoprotein, and a member of the immunoglobulin superfamily of cell surface receptors. PECAM-1 is constitutively expressed on the surface of endothelial cells where it is concentrated at cell junctions. PECAM-1 is also expressed at low levels on all leukocytes and platelets. Homotypic interaction of CD31 is important in cell-cell interaction, cell-matrix interaction and signal transduction. View All» Species Reactivity: Human View All» Species Reactivity Note: Human View All» Application Notes: Immunohistochemistry Analysis: 1:250 - 500 dilution from a previous lot detected PECAM1 in human uterus and tonsil tissue.Flow Cytometry: 1:70 dilution from a previous lot was used on FC. View All» Control: THP-1 and Jurkat cell lysates View All» Quality Assurance: Evaluated by Western Blot on THP-1 and Jurkat cell lysates.Western Blot Analysis: 1:5,000 - 20,000 dilution of this antibody was used to detect PECAM1 in THP-1 and Jurkat cell lysates. View All» Purification Method: Unpurified View All» Presentation: Rabbit Monoclonal in buffer containing 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl containing 40% Glycerol, 0.01% sodium azide and 0.05% BSA. View All» Storage Conditions: Stable for 1 year at -20ºC from date of receipt.Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerolcontaining solutions to become frozen during storage. View All» UniProt Number: P16284 View All» Entrez Gene Number: NP_000433.3 View All» Gene Symbol:

• CD31

• CD31/EndoCAM

• EndoCAM

• GPIIA'

• PECAM-1
  View All» Alternate Names:
  • CD31 antigen

  • PECAM-1, CD31/EndoCAM

  • adhesion molecule

  • platelet/endothelial cell adhesion mo
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Western Blotting

    • Immunohistochemistry (Paraffin)

    • Flow Cytometry
      View All» UniProt Summary: FUNCTION: This protein is a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions.SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. TISSUE SPECIFICITY: Long isoform predominates all tissues examined, isoform Delta12 was detected only in trachea and isoform Delta14-15 only in lung, isoform Delta14 was detected in all tissues examined with the strongest expression in heart. PTM: Phosphorylated on Ser and Tyr residues after cellular activation. SEQUENCE SIMILARITIES: Contains 6 Ig-like C2-type (immunoglobulin-like) domains. View All» Product Name: Anti-PECAM-1 [CD31], clone EP3095, Rabbit Monoclonal View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Unpurified View All» Host: Rabbit View All»
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