货号：04-1126

品牌：Merck Millipore

规格：

目录价：￥4118.00

市场价格：￥3500.30

会员价格：￥3294.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-N-cadherin Antibody, C-terminus clone EPR1792Y Rabbit | 04-1126 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes N-cadherin. View All» Molecular Weight: ~ 140 kDa View All» Epitope: C-terminus View All» Immunogen: Synthetic peptide corresponding to residues on the C-terminus of human N-cadherin. View All» Clone: EPR1792Y View All» Isotype: IgG View All» Background Information: Cadherins constitute a family of transmembrane glycoproteins involved in Ca2+-dependent cell-cell interactions. The members of this family are differentially expressed in various tissues. They function in the maintenance of tissue integrity and morphogenesis. Cadherins are divided into type I and type II subgroups. Type I cadherins include epithelial cadherin (E-cadherin, cadherin-1 or uvomorulin), neural cadherin (N-cadherin or cadherin-2), placental cadherin (P-cadherin or cadherin-3) and retinal cadherin (R-cadherin or cadherin-4), whereas kidney cadherin (K-cadherin or cadherin-6) and osteoblast cadherin (OB-cadherin or cadherin-11) are type II cadherins. View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Species Reactivity Note: Human, mouse, and rat. View All» Application Notes: Immunohistochemistry Analysis: 1:100 dilution from a previous lot detected N-cadherin in human cervical carcinoma tissue.Immunocytochemistry Analysis: 1:100-250 dilution from a previous lot detected N-cadherin in HeLa cell lysate.Immunoprecipitation: 1:40 dilution from a previous lot was used on IP.Flow Cytometry: 1:30 dilution from a previous lot was used on FC. View All» Control: C6 cell lysate View All» Quality Assurance: Evaluated by Western Blot on C6 cell lysate.Western Blot Analysis: 1:50,000 dilution of this antibody was used to detect N-cadherin in C6 cell lysate. View All» Purification Method: Unpurified View All» Presentation: Cell culture supernatant containing Rabbit Monoclonal antibody in buffer containing 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl containing 40% Glycerol, 0.01% sodium azide and 0.05% BSA. View All» Storage Conditions: Stable for 1 year at -20ºC from date of receipt.Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage. View All» UniProt Number: P19022 View All» Entrez Gene Number: P19022 View All» Gene Symbol:
  • CD325

  • CDHN

  • CDw325

  • N-cadherin

  • NCAD
    View All» Alternate Names:
    • CD325 antigen

    • N-cadherin 1

    • Neural cadherin

    • cadherin 2, N-cadherin (neuronal)

    • cadherin 2, type 1

    • cadherin 2, type 1, N-cadherin (neuronal)

    • calcium-dependent adhesion protein, neuronal
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Immunohistochemistry (Paraffin)

      • Immunocytochemistry

      • Immunoprecipitation

      • Flow Cytometry
        View All» UniProt Summary: FUNCTION: Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH2 may be involved in neuronal recognition mechanism.SUBUNIT STRUCTURE: Interacts with CDCP1. SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein. SEQUENCE SIMILARITIES: Contains 5 cadherin domains. View All» Product Name: Anti-N-cadherin, C-terminus clone EPR1792Y Rabbit Monoclonal View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Culture Supernatant View All» Host: Rabbit View All»
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