货号：MAB3878

品牌：Merck Millipore

规格：100Ug

目录价：￥5409.00

市场价格：￥4597.65

会员价格：￥4327.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-MyoD1 Antibody | MAB3878 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Recognizes MyoD1. The epitope is localized to amino acids 3-56 in the N-terminus of mouse MyoD1 protein. View All» Molecular Weight: ~ 45 kDa View All» Immunogen: Recombinant protein from mouse MyoD1. View All» Clone: 5.2F View All» Isotype: IgG2a View All» Species Reactivity:

• Chicken

• Human

• Mouse

• Rat
  View All» Application Notes: Western blot: 1 μg/mL. Reacts with the ~45 kD protein. Immunohistochemistry on frozen and formalin-fixed, paraffin embedded tissue: 2-4 μg/mL. Immunocytochemistry Immunoprecipitation: 2 μg/mg of protein lysate Optimal working dilutions must be determined by end user. View All» Control: Fetal Muscle, Rhabdomyosarcoma View All» Purification Method: Protein A purfied View All» Presentation: Protein A Purified mouse immunoglobulin in 20 mM sodium phosphate, 250 mM NaCl, pH. 7.6, with 0.1% sodium azide as a preservative. View All» Storage Conditions: Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. View All» UniProt Number: P15172 View All» Entrez Gene Number: NM_002478.4 View All» Gene Symbol:
  • MYOD1

  • MYOD

  • PUM

  • Myf-3

  • MYF3
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunocytochemistry

    • Immunohistochemistry

    • Immunoprecipitation

    • Western Blotting
      View All» Entrez Gene Summary: This gene encodes a nuclear protein that belongs to the basic helix-loop-helix family of transcription factors and the myogenic factors subfamily. It regulates muscle cell differentiation by inducing cell cycle arrest, a prerequisite for myogenic initiation. The protein is also involved in muscle regeneration. It activates its own transcription which may stabilize commitment to myogenesis. View All» UniProt Summary: FUNCTION: SwissProt: P15172 # Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Activates muscle-specific promoters. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins (By similarity).SIZE: 319 amino acids; 34490 Da SUBUNIT: Efficient DNA binding requires dimerization with another bHLH protein. Seems to form active heterodimers with ITF-2. Interacts with SUV39H1.SUBCELLULAR LOCATION: Nucleus.PTM: Acetylated by a complex containing EP300 and PCAF. The acetylation is essential to activate target genes. Conversely, its deacetylation by SIRT1 inhibits its function (By similarity). & Ubiquitinated on the N-terminus; which is required for proteasomal degradation.SIMILARITY: SwissProt: P15172 ## Contains 1 basic helix-loop-helix (bHLH) domain. View All» Brand Family: Chemicon View All» Product Name: Anti-MyoD1 Antibody | MAB3878 View All» Concentration: 1 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Mouse View All»
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