货号：MAB4122

品牌：Merck Millipore

规格：100Ug

目录价：￥4836.00

市场价格：￥4110.60

会员价格：￥3868.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Multi-Drug Resistance Related Protein Antibody, clone MRPm6 | MAB4122 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: MRPm6 reacts with an internal epitope of MRP, a 180-195 kDa transmembrane transporter protein overexpressed in various human non-P-glycoprotein MDR tumor cell lines. MRPm6 was raised against a bacterial fusion protein of MRP, containing a segment of 170 amino acids in the carboxy terminal end and part of the carboxy proximal nucleotide binding domain of the protein. MRPm6 does not cross-react with the human MDR1 and MDR3 gene products (Flens et al., 1994). View All» Clone: MRPm6 View All» Isotype: IgG1 View All» Species Reactivity: Human View All» Application Notes: Western blot Flow Cytometry Immunohistochemistry on frozen and paraffin embedded tissue sections: 1:20. Note: For cellular detection permeabilization is required. Optimal working dilutions must be determined by end user. View All» Presentation: Tissue Culture Supernatant. Liquid containing 0.1% sodium azide and 0.7% BSA. View All» Storage Conditions: Store at -20°C in undiluted aliquots. May be stored at 2-8°C for short term use. Avoid repeated freeze-thaw cycles. View All» UniProt Number: P33527 View All» Entrez Gene Number:

• NM_019901.1

• NM_019902.1

• NM_004996.3

• NM_019862.2

• NM_019898.2

• NM_019899.2

• NM_019900.2
  View All» Gene Symbol:
  • ABCC1

  • 4transporter)

  • ABC29

  • GS-X

  • ABCC

  • MRP1

  • DKFZp781G125

  • MRP

  • DKFZp686N04233
    View All» Alternate Names: MRP View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Flow Cytometry

    • Western Blotting

    • Immunohistochemistry (Paraffin)
      View All» Entrez Gene Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternative splicing by exon deletion results in several splice variants but maintains the original open reading frame in all forms. View All» UniProt Summary: FUNCTION: SwissProt: P33527 # May participate directly in the active transport of drugs into subcellular organelles or influence drug distribution indirectly. Confers resistance to anticancer drugs. Transports LTC4. May protect milk against xenobiotics (By similarity).SIZE: 1531 amino acids; 171561 Da SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.TISSUE SPECIFICITY: Lung, testis and peripheral blood mononuclear cells.SIMILARITY: SwissProt: P33527 ## Belongs to the ABC transporter family. Conjugate transporter (TC 3.A.1.208) subfamily. & Contains 2 ABC transmembrane type-1 domains. & Contains 2 ABC transporter domains. View All» Brand Family: Chemicon View All» Product Name: Anti-Multi-Drug Resistance Related Protein Antibody, clone MRPm6 | MAB4122 View All» Concentration: Approximately 500 μg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Culture Supernatant View All» Host: Mouse View All»
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