货号：04-158

品牌：Merck Millipore

规格：EA

目录价：￥3108.00

市场价格：￥2641.80

会员价格：￥2486.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-CD137L/4-1BBL Antibody, clone TKS-1 | 04-158 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes CD137L/4-1BBL. View All» Molecular Weight: ~ 34 kDa View All» Epitope: Unknown View All» Immunogen: Mouse 4-1BBL cDNA-transfected NRK cells. View All» Clone: TKS-1 View All» Isotype: IgG2aκ View All» Background Information: Tumor necrosis factor receptor ligand superfamily member 9 (also known as CD137L, 4-1BBL or 4-1BB ligand) is a ligand for CD137, a member of the tumor necrosis factor (TNF) receptor family and is induced by lymphocyte activation (ILA). CD137 can be expressed by activated T cells, but more so on CD8 rather than on CD4 T cells. In addition, CD137 expression is found on dendritic cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. CD137 interacts with TRAF1, TRAF2 and TRAF3, as well as LRR-repeat protein 1/LRR-1. CD137 exhibits costimulatory activity for activated T cells, where the crosslinking of CD137 enhances T cell proliferation, IL-2 secretion survival and cytolytic activity. CD137 may also enhance immune activity towards tumor suppression. View All» Species Reactivity: Mouse View All» Species Reactivity Note: Demonstrated to react with mouse. View All» Control: RAW264.7 cells View All» Quality Assurance: Evaluated by Flow Cytometry in RAW264.7 cells.Flow Cytometry Analysis: 1 µg of this antibody detected CD137L/4-1BBL in RAW264.7 cells. View All» Purification Method: Protein G purfied View All» Presentation: Purified rat monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: P41274 View All» Entrez Gene Number: NP_033430 View All» Gene Symbol:

• TNFS9

• 4-1BB-L

• 4-1BBL

• CD137L
  View All» Alternate Names:
  • 4-1BB ligand

  • homolog of mouse 4-1BB-L

  • receptor 4-1BB ligand

  • tumor necrosis factor (ligand) superfamily, member 9
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Flow Cytometry View All» UniProt Summary: FUNCTION: Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.SUBUNIT STRUCTURE: Homotrimer Potential.SUBCELLULAR LOCATION: Membrane; Single-pass type II membrane protein. SEQUENCE SIMILARITIES: Belongs to the tumor necrosis factor family. View All» Product Name: Anti-CD137L/4-1BBL, clone TKS-1 View All» Concentration: 0.5 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Rat View All»
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