货号：04-159

品牌：Merck Millipore

规格：EA

目录价：￥3108.00

市场价格：￥2641.80

会员价格：￥2486.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-CD153/CD30L Antibody, clone RM153 | 04-159 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes mouse CD153/CD30L. View All» Molecular Weight: ~ 27 kDa View All» Epitope: Unknown View All» Immunogen: Mouse CD30L cDNA-transfected NRK cells. View All» Clone: RM153 View All» Isotype: IgG2aκ View All» Background Information: CD153, also known as (CD30 ligand or CD30L), is a type II membrane-associated glycoprotein belonging to TNFSF. CD153 is expressed on both CD4+ Th1 and Th2 cells, and may be expressed on macrophages, dendritic cells (DC), B cells, and unique CD4+CD3–CD11c– accessory cells, which are the adult equivalent of inducer cells for the development of lymph node and Peyer’s patches in ontogeny. Several members of the TNF superfamily (TNFSF) have been shown to regulate the fate of T cell immunity. CD30, the receptor for CD30L, and belonging to the TNFRSF, was reported to be expressed preferentially by activated or memory Th2 cells but not by resting B or T cells. CD30L/CD30 signaling was thought to be involved in Th2 cell responses and Th2-associated diseases. However, a number of studies suggest that CD30L/CD30 signaling is also linked to Th1 cell responses and Th1-associated diseases. Furthermore, there are several lines of evidence that naturally occurring regulatory T cells suppressed allograft rejection mediated by memory CD4+ T cells via a CD30-dependent mechanism (Tang, C., et al, 2008). View All» Species Reactivity: Mouse View All» Species Reactivity Note: Demonstrated to react with mouse. View All» Application Notes: Immunoprecipitation Analysis: A previous lot was used by an independent laboratory in IP (Shimozato, O., et al., 1999; Seko, Y., et al., 2001; Akiba, H., et al., 2000; Zeiser, R., et al., 2007).Immunohistochemistry Analysis: A previous lot was used by an independent laboratory in IH (Shimozato, O., et al., 1999; Seko, Y., et al., 2001; Akiba, H., et al., 2000; Zeiser, R., et al., 2007). View All» Control: PMA-stimulated BALB/c splenocytes View All» Quality Assurance: Evaluated by Flow Cytometry in PMA-stimulated BALB/c splenocytes.Flow Cytometry Analysis: 1 µg of this antibody detected CD153/CD30L in PMA-stimulated BALB/c splenocytes. View All» Purification Method: Protein G purfied View All» Presentation: Purified rat monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: P32972 View All» Entrez Gene Number: NP_033429 View All» Gene Symbol:

• TNFSF8

• CD153

• CD30-L

• CD30L

• CD30LG
  View All» Alternate Names:
  • CD153 antigen

  • CD30 antigen ligand

  • CD30 ligand

  • tumor necrosis factor (ligand) superfamily, member 8
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Flow Cytometry

    • Immunohistochemistry

    • Immunoprecipitation
      View All» UniProt Summary: FUNCTION: Cytokine that binds to TNFRSF8/CD30. Induces proliferation of T-cells.SUBUNIT STRUCTURE: Homotrimer Probable.SUBCELLULAR LOCATION: Membrane; Single-pass type II membrane protein. SEQUENCE SIMILARITIES: Belongs to the tumor necrosis factor family. View All» Product Name: Anti-CD153/CD30L, clone RM153 View All» Concentration: 0.5 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Rat View All»
      © 金山科研平台是专业的授权总代理区域代理经销平台。
      © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
      © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
      © 本文地址：https://www.16ao.com/thread-131569.htm
      © Merck Millipore代理04-159 Anti-CD153/CD30L, clone RM153，产品报价联系微信jinshanbio