货号:04-1590
品牌:Merck Millipore
规格:EA
目录价:¥3144.00
市场价格:¥2672.40
会员价格:¥2515.20
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Description:
Anti-CCR9 Antibody, clone 9B1 | 04-1590
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Promotional Text:
Special Shipping Offer on Antibodies100% Performance Guaranteed
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Specificity:
This antibody recognizes CCR9 at the N-terminus.
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Molecular Weight:
~42 kDa (expected MW)
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Epitope:
N-terminus
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Immunogen:
KLH-conjugated linear peptide corresponding to the N-terminus of mouse CCR9.
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Clone:
9B1
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Isotype:
IgG2aκ
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Background Information:
CCR9 (chemokine receptor 9) is a chemokine receptor that is expressed in thymocytes and T lymphocytes from the small intestine and colon but not in lymphocytes from tonsils, lung, inflamed liver, normal or inflamed skin, inflamed synovium and synovial fluid, breast milk, and seminal fluid (Kunkel et al., 2000). CCR9 is not detected in natural killer cells, monocytes, eosinophils, basophils, and neutrophils. CCR9 binds TECK (thymus-expressed chemokine), a CC chemokine expressed in thymus and small intestine. TECK chemoattracts dendritic cells, thymocytes, and activated macrophages.
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Species Reactivity:
Mouse
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Species Reactivity Note:
Demonstrated to react with mouse.
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Control:
CD8+ mouse thymocytes
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Quality Assurance:
Evaluated by Flow Cytometry in CD8+ mouse thymocytes.Flow Cytometry Analysis: 1 µg of this antibody detected CCR9 in CD8+ mouse thymocytes.
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Purification Method:
Protein G purfied
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Presentation:
Purified rat monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.
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Storage Conditions:
Stable for 1 year at 2-8°C from date of receipt.
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UniProt Number:
Q9WUT7
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Entrez Gene Number:
NP_001160097
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Gene Symbol:
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CCR9
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GPR28
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CC-CKR-9
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D6
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GPR-9-6
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CCR10
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CCR-9
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CMKBR9
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CCBP2
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Alternate Names:
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chemokine (C-C motif) receptor 9
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CDw199 antigen
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G-protein coupled receptor 28
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G protein-coupled receptor 28
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Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Flow Cytometry
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UniProt Summary:
FUNCTION: Receptor for chemokine SCYA25/TECK. Subsequently transduces a signal by increasing the intracellular calcium ions level.SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. TISSUE SPECIFICTY: Highly expressed in the thymus and low in lymph nodes and spleen.SEQUENCE SIMILARITIES: Belongs to the G-protein coupled receptor 1 family.
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Product Name:
Anti-CCR9, clone 9B1
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Concentration:
1.0 mg/mL
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Antibody Type:
Monoclonal Antibody
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Qty/Pk:
100 μg
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Format:
Purified
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Host:
Rat
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