货号：04-1624

品牌：Merck Millipore

规格：100Ug

目录价：￥5207.00

市场价格：￥4425.95

会员价格：￥4165.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Centrin Antibody, clone 20H5 | 04-1624 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes the C-terminus of Centrin. View All» Molecular Weight: ~ 20 kDa View All» Epitope: C-terminus View All» Immunogen: Recombinant protein corresponding to the C-terminus of Chlamydomonas Centrin. View All» Clone: 20H5 View All» Isotype: IgG2aκ View All» Background Information: Centrin is a key regulator of centriole duplication. This protein is localized to the centrosome of interphase cells. During mitosis, centrin redistributes to the spindle poles, consistent with dynamic changes of the centrosome during the cell cycle. Current research suggests centrin exerts spatial and temporal control over centriole duplication through its role as a component of centriole precursor structures and through periodic cell-cycle specific changes in its abundance. View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Species Reactivity Note: Demonstrated to react in Human. View All» Application Notes: Immunocytochemistry Analysis: Manandhar, G., et al. (1999). Cell Motil Cytoskeleton. 43(2):137-144. View All» Control: HeLa cell lysate View All» Quality Assurance: Evaluated by Western Blot in HeLa cell lysate.Western Blot Analysis: 1 µg/ml of this antibody detected Centrin on 10 µg of HeLa cell lysate. View All» Purification Method: Protein G purfied View All» Presentation: Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q12798 View All» Entrez Gene Number: NP_004057 View All» Gene Symbol:
  • CEN1

  • CETN

  • Centrin-1
    View All» Alternate Names:
    • Caltractin isoform 2

    • EF-hand protein

    • calcium binding protein

    • centrin 1

    • centrin, EF-hand protein, 1
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Immunoprecipitation

      • Immunocytochemistry
        View All» Entrez Gene Summary: The protein encoded by this gene plays important roles in the determination of centrosome position and segregation, and in the process of microtubule severing. This encoded protein is localized to the centrosome of interphase cells, and redistributes to the region of the spindle poles during mitosis, reflecting the dynamic behavior of the centrosome during the cell cycle. View All» UniProt Summary: FUNCTION: Plays a fundamental role in microtubule-organizing center structure and function.SUBUNIT STRUCTURE: Monomer By similarity.SUBCELLULAR LOCATION: Cytoplasm › cytoskeleton › centrosome. Note: Centrosome of interphase and mitotic cells.MISCELLANEOUS: Binds two moles of calcium per mole of protein.SEQUENCE SIMLARITIES: Belongs to the centrin family.Contains 4 EF-hand domains. View All» Product Name: Anti-Centrin, clone 20H5 View All» Concentration: 1.0 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Mouse View All»
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        © Merck Millipore代理04-1624 Anti-Centrin Antibody, clone 20H5;抗-Centrin抗体，克隆20H5store at +2℃ to +8℃，产品报价联系微信jinshanbio