货号：04-215

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-CCRL1/CC-CKR-11 Antibody | 04-215 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: This antibody recognizes CCRL1/CC-CKR-11 at the N-terminus. View All» Molecular Weight: 45 kDa View All» Epitope: N-terminus View All» Immunogen: A synthetic peptide corresponding to residues in N-terminus (extracellular domain) of human CCRL1/CC-CKR-11 at the N-terminus. View All» Isotype: IgG View All» Background Information: Chemokine (C-C motif) receptor-like 1 (CCRL1) also known as CC-CKR-11, is a G-protein coupled receptor (GPCR) for C-C type cytokines. As such it is a seven transmembrane receptor that binds chemokines. As the CCR denotes, the ligand binds adjacent to the first 2 cysteines. It is known to be predominantly expressed in the heart with other areas of expression including lung, pancreas, colon, and small intestine. CCRL1 is known to bind the dendritic and T-cell chemokines that include CCL12, CCL21, and CCL25. View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Quality Assurance: Routinely evaluated by immunoblot. View All» Presentation: 100 μL of rabbit monoclonal IgG in 60% storage buffer (50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 0.01% sodium azide and 0.05% BSA) and 40% glycerol. View All» Storage Conditions: 2 years at -20°C from date of shipment View All» UniProt Number: Q9NPB9 View All» Entrez Gene Number: NM_016557 View All» Gene Symbol: Q9NPB9 View All» Key Applications:
  • Immunoprecipitation

  • Western Blotting

  • Immunocytochemistry
    View All» Entrez Gene Summary: The protein encoded by this gene is a member of the G protein-coupled receptor family, and is a receptor for C-C type chemokines. This receptor has been shown to bind dendritic cell- and T cell-activated chemokines including CCL19/ELC, CCL21/SLC, and CCL25/TECK. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq] View All» UniProt Summary: Function: Receptor for CCL2, CCL8, CCL13, CCL19, CCL21 and CCL25.Subcellular location:Cell membrane; Multi-pass membrane protein. Tissue specificity: Predominantly expressed in heart. Lower expression in lung, pancreas, spleen, colon, skeletal muscle and small intestine.Sequence similarities: Belongs to the G-protein coupled receptor 1 family. View All» Brand Family: Upstate View All» Product Name: Anti-CCRL1/CC-CKR-11 (N-term), clone E100 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μL View All» Format: Culture Supernatant View All» Host: Rabbit View All»
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