货号：04-322

品牌：Merck Millipore

规格：

目录价：￥3662.00

市场价格：￥3112.70

会员价格：￥2929.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Acetyl CoA Carboxylase 1 Antibody, Rabbit | 04-322 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: Recognizes Acetyl CoA Carboxylase 1 View All» Molecular Weight: 265 kDa View All» Immunogen: KLH-conjugated synthetic peptide corresponding to human Acetyl CoA Carboxylase 1 View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Quality Assurance: Routinely evaluated by immunoblot. View All» Presentation: 100 μL of rabbit monoclonal IgG in 30 mM Tris-Glycine (pH 7.4), 0.09 M NaCl, 0.006% sodium azide, 0.03% BSA and 40% glycerol. View All» Storage Conditions: Stable for 2 years at -20°C from date of shipment. View All» UniProt Number: Q13085 View All» Entrez Gene Number:
  • NM_198834.1

  • NM_198836.1

  • NM_198837.1

  • NM_198838.1

  • NM_198839.1
    View All» Gene Symbol:
    • ACACA

    • ACC-alpha

    • ACCA

    • ACC

    • ACC1

    • ACAC
      View All» Alternate Names: ACACA, ACAC, ACC, ACC1, ACCA, acetyl-Coenzyme A carboxylase alpha View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Immunohistochemistry (Paraffin)
        View All» Entrez Gene Summary: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. View All» UniProt Summary: FUNCTION: SwissProt: Q13085 # Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.COFACTOR: Biotin. & Binds 2 manganese ions per subunit.SIZE: 2346 amino acids; 265554 Da SUBUNIT: Interacts in its inactive phosphorylated form with the BRCT domains of BRCA1 which prevents ACACA dephosphorylation and inhibits lipid synthesis.SUBCELLULAR LOCATION: Cytoplasm.TISSUE SPECIFICITY: Expressed in brain, placental, skeletal muscle, renal, pancreatic and adipose tissues; expressed at low level in pulmonary tissue; not detected in the liver.PTM: Phosphorylation on Ser-1263 is required for interaction with BRCA1.SIMILARITY: SwissProt: Q13085 ## Contains 1 ATP-grasp domain. & Contains 1 biotin carboxylation domain. & Contains 1 biotinyl-binding domain. & Contains 1 carboxyltransferase domain. View All» Brand Family: Upstate View All» Product Name: Anti-Acetyl CoA Carboxylase 1 Antibody, Rabbit | 04-322 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Purified View All» Host: Rabbit View All»
        © 金山科研平台是专业的授权总代理区域代理经销平台。
        © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
        © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
        © 本文地址：https://www.16ao.com/thread-131709.htm
        © Merck Millipore代理04-322 Anti-Acetyl CoA Carboxylase 1, (Rabbit Monoclonal)，产品报价联系微信jinshanbio