货号：MAB4401A4

品牌：Merck Millipore

规格：

目录价：￥4858.00

市场价格：￥4129.30

会员价格：￥3886.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Oct-4 Antibody, clone 10H11.2, Alexa Fluor® 488 conjugate | MAB4401A4 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes human Oct-4. Antibody is not reactive with mouse Oct-4 protein. View All» Molecular Weight: The unconjugated parent antibody (Catalog No. MAB4401) has an observed MW at 44 kDA. View All» Immunogen: Recombinant GST fusion protein, human Oct-4 (aa 1-134). View All» Isotype: IgG1 View All» Background Information: Octamer-4 (Oct-4), a member of the POU family of transcription factors, has been demonstrated to be vital for the formation of self-renewing pluripotent stem cells. During embryogenesis expression of Oct-4 is limited to pluripotent cells of the inner cell mass (ICM) that contribute to the formation of all fetal cell types. This relationship between Oct-4 and pluripotency has seen this transcription factor emerge as a marker of pluripotent stem cells. Undifferentiated human and murine pluripotent Embryonic Stem (ES) and Embryonic Carcinoma (EC) cells express Oct-4. Additionally, murine Embryonic Germ (EG) cells are also known to express Oct-4. Following stem cell differentiation, the level of Oct-4 expression decreases. Oct-4 has been indentified as one of the key genes used to reprogram somatic cells into induced pluripotent stem cells (iPS cells). View All» Species Reactivity: Human View All» Species Reactivity Note: Demonstrated to react with Human. Antibody is not reactive with mouse Oct-4 protein. View All» Application Notes: Evaluated by Immunocytochemistry in mouse embryonic stem cells (SCR012). Immunocytochemsitry Analysis: A 1:100 dilution of this antibody did not detect Oct-4 in mouse embryonic stem cells (SCR012). View All» Control: H9 human embryonic stem cells. View All» Quality Assurance: Evaluated by Immunocytochemistry in H9 human embryonic stem cells. Immunocytochemsitry Analysis: A 1:100 dilution of this antibody detected Oct-4 in H9 human embryonic stem cells. View All» Purification Method: Protein A purified View All» Presentation: Purified mouse monoclonal IgG1 conjugated to Alexa Fluor® 488 in PBS with 0.1% sodium azide and 15mg/ml BSA. View All» Storage Conditions: Maintain refrigerated at 2-8ºC protected from light in undiluted aliquots for up to 6 months from date of receipt. View All» UniProt Number: Q01860 View All» Entrez Gene Number: NP_002692 View All» Gene Symbol:

• POU5F1

• Oct-3

• MGC22487

• Oct4

• OTF4

• OTF3

• OCT3

• OCT4

• Oct-4
  View All» Alternate Names:
  • OCT3/4

  • Octamer-binding transcription factor 3

  • POU class 5 homeobox 1

  • POU domain, class 5, transcription factor 1

  • POU-type homeodomain-containing DNA-binding protein

  • octamer-binding transcription factor-3
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Immunocytochemistry View All» Product Name: Anti-Oct-4, clone 10H11.2, Alexa Fluor® 488 conjugate View All» Concentration: 0.5 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Format: AlexaFluor®488 View All» Host: Mouse View All»
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