货号：04-369

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-IRR α subunit Antibody, rabbit | 04-369 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: Recognizes the IRR alpha subunit View All» Molecular Weight: 80/144 kDa View All» Immunogen: KLH-conjugated synthetic peptide near the N-terminus of human IRR alpha subunit. View All» Isotype: IgG View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Application Notes: Immunoblot Analysis: A 1:2,000 dilution of the lot detected IRR alpha subunit in lysates from PC12, MCF-7, HeLa and SHSY5Y cells. Immunohistochemistry: A 1:50-1:100 dilution of this antibody was used in immunohistochemical analysis of Paraffin-embedded human kidney tissue using the anti-IRR alpha subunit antibody. View All» Quality Assurance: Routinely evaluated by immunoblot. View All» Purification Method: Serum View All» Presentation: 100 µL of rabbit monoclonal IgG in 30 mM Tris-Glycine (pH 7.4), 0.09 M NaCl, 0.006% sodium azide and 0.03% BSA and 40% glycerol. View All» Storage Conditions: 2 years at -20°C from date of shipment View All» UniProt Number: P14616 View All» Entrez Gene Number: NM_014215.1 View All» Gene Symbol:
  • INSRR

  • IRR
    View All» Alternate Names: INSRR View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunoprecipitation

    • Western Blotting
      View All» UniProt Summary: FUNCTION: SwissProt: P14616 # This receptor probably binds an insulin related protein and has a tyrosine-protein kinase activity. It phosphorylates the insulin receptor substrates IRS-1 and IRS-2.SIZE: 1297 amino acids; 143720 Da SUBUNIT: Probable tetramer of 2 alpha and 2 beta chains linked by disulfide bonds. The alpha chains contribute to the formation of the ligand-binding domain, while the beta chains carry the kinase domain.SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.SIMILARITY: SwissProt: P14616 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily. & Contains 4 fibronectin type-III domains. & Contains 1 protein kinase domain. View All» Brand Family: Upstate View All» Product Name: Anti-IRR α subunit Antibody, rabbit | 04-369 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Purified View All» Host: Rabbit View All»
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