货号：04-378

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-MEKK2 CT Antibody | 04-378 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: Recognizes the C-terminal domain of MEKK2. View All» Molecular Weight: 70 kDa View All» Epitope: C-terminus View All» Immunogen: KLH-conjugated synthetic peptide corresponding to the C-terminal region of human MEKK2. View All» Isotype: IgG View All» Species Reactivity: Human View All» Non-Reactive Species:

• Mouse

• Rat
  View All» Application Notes: Wetsren Blot: 1:1000. Immunoprecipitation: 1:50. The use of protein G is recommended. Flow Cytometry: 1:50. Immunohistochemistry: 1:50 on paraffin embedded tissue sections of human breast carcinoma. Immunofluorescence: 1:50-1:100. Paraformaldehyde fixation is recommended. Optimal working dilutions must be determined by the end user. View All» Quality Assurance: Routinely evaluated by immunoblot analysis. View All» Purification Method: Protein G purfied View All» Presentation: Rabbit monoclonal IgG in 30 mM Tris-Glycine (pH 7.4), 90mM NaCl, 0.006% sodium azide, 0.03% BSA and 40% glycerol. View All» Storage Conditions: 1 year at -20°C from date of shipment. View All» UniProt Number: Q9Y2U5 View All» Entrez Gene Number: NM_006609.3 View All» Gene Symbol:
  • MAP3K2

  • MEKK2B

  • MAPKKK2

  • MEKK2
    View All» Alternate Names: MAP3K2, MEKK2B View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Flow Cytometry

    • Immunocytochemistry

    • Immunohistochemistry (Paraffin)

    • Immunoprecipitation

    • Western Blotting
      View All» Entrez Gene Summary: The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process. View All» UniProt Summary: FUNCTION: SwissProt: Q9Y2U5 # Component of a protein kinase signal transduction cascade. Regulates the JNK and ERK5 pathways by phosphorylating and activating MAP2K5 and MAP2K7 (By similarity). Plays a role in caveolae kiss-and-run dynamics.COFACTOR: Magnesium.SIZE: 619 amino acids; 69741 Da SUBUNIT: Binds both upstream activators and downstream substrates in multimolecular complexes.SUBCELLULAR LOCATION: Cytoplasm. Note=Upon EGF stimulation, translocates into the nucleus.PTM: Autophosphorylated (By similarity).SIMILARITY: SwissProt: Q9Y2U5 ## Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. & Contains 1 OPR domain. & Contains 1 protein kinase domain. View All» Brand Family: Upstate View All» Product Name: Anti-MEKK2 CT Antibody | 04-378 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Purified View All» Host: Rabbit View All»
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