货号：04-383

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-MKK6 NT Antibody | 04-383 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Recognizes MKK6. View All» Molecular Weight: 36 kDa View All» Epitope: N-terminus View All» Immunogen: KLH-conjugated synthetic peptide corresponding to residues in the N-term of human MKK6. View All» Isotype: IgG View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Application Notes: Western Blot: 1:10,000. Immunoprecipitation: 1:50. The use of protein G agarose is recommended. Optimal working dilutions must be determined by the end user. View All» Control: POSITIVE: HeLa cells. View All» Quality Assurance: Routinely evaluated by immunoblot analysis. View All» Purification Method: Protein G purfied View All» Presentation: Rabbit monoclonal IgG in 30 mM Tris-Glycine (pH 7.4), 90 mM NaCl, 0.006% sodium azide, 0.03% BSA and 40% glycerol. View All» Storage Conditions: 2 years at -20°C from date of shipment. View All» UniProt Number: P52564 View All» Entrez Gene Number: NM_002758.3 View All» Gene Symbol:
  • MAP2K6

  • MEK6

  • PRKMK6

  • SAPKK3

  • MAPKK6

  • MKK6
    View All» Alternate Names: MAPKK6, MEK6, MKK6, PRKMK6, SAPKK3 View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunoprecipitation

    • Western Blotting
      View All» Entrez Gene Summary: This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. View All» UniProt Summary: FUNCTION: SwissProt: P52564 # Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in MAP kinase p38 exclusively.SIZE: 334 amino acids; 37492 Da SUBUNIT: Interacts with Yersinia yopJ.TISSUE SPECIFICITY: Isoform 2 is only expressed in skeletal muscle. Isoform 1, on the other hand, is found in skeletal muscle, heart, and in lesser extent in liver or pancreas.PTM: Weakly autophosphorylated. & Acetylation of Ser-207 and Thr-211 by Yersinia yopJ prevents phosphorylation and activation, thus blocking the MAPK signaling pathway.SIMILARITY: SwissProt: P52564 ## Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily. & Contains 1 protein kinase domain. View All» Brand Family: Chemicon View All» Product Name: Anti-MKK6 NT Antibody | 04-383 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Purified View All» Host: Rabbit View All»
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