货号：MAB5256A5

品牌：Merck Millipore

规格：100UL

目录价：￥6434.00

市场价格：￥5468.90

会员价格：￥5147.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Neurofilament 200kDa Antibody, clone NE14, Alexa Fluor® 555 Conjugate | MAB5256A5 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Immunogen: Purified neurofilament polypeptides (Debus et al., 1983). View All» Clone: NE14 View All» Isotype: IgG1 View All» Background Information: Neurofilaments are a type of intermediate filament that serve as major elements of the cytoskeleton supporting the axon cytoplasm. They are the most abundant fibrillar components of the axon, being on average 3-10 times more frequent than axonal microtubules. Neurofilaments (10nm in dia.) are built from three intertwined protofibrils which are themselves composed of two tetrameric protofilament complexs of monomeric proteins. The neurofilament triplet proteins (68/70, 160, and 200 kDa) occur in both the central and peripheral nervous system and are usually neuron specific. The 68/70 kDa NF-L protein can self-assemble into a filamentous structure, however the 160 kDa NF-M and 200 kDa NF-H proteins require the presence of the 68/70 kDa NF-L protein to co-assemble. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas and neuroblastomas stain positively for neurofilaments. Although typically restricted to neurons, neurofilaments have been detected in paragangliomas and adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilaments. For more neurofilament information and epitope maps, search "neurofilament" on our website. View All» Species Reactivity:

• Rat

• Mouse

• Pig

• Human
  View All» Species Reactivity Note: Demonstrated to react with Mouse, and Rat. Predicted to react with Porcine based on immunogen design. Predicted to react with Human based on 100% sequence homology. Unconjugated Anti-Neurofilament has been shown to work with multiple species including Human and Porcine. View All» Application Notes: Immunohistochemistry Analysis: A 1:100 dilution from a representative lot detected Neurofilament in adult mouse brain cryosections. View All» Control: Rat E18 primary cortex cells View All» Quality Assurance: Evaluated by Immunocytochemistry in rat E18 primary cortex cells.Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected Neurofilament in rat E18 primary cortex cells. View All» Purification Method: Protein A purified View All» Presentation: Purified mouse monoclonal IgG1 conjugated to Alexa Fluor® 555 in PBS with 0.1% sodium azide and 15 mg/mL BSA. View All» Storage Conditions: Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt. View All» UniProt Number: P12036 View All» Entrez Gene Number: NP_066554 View All» Gene Symbol:
  • NEFH

  • NFH
    View All» Alternate Names:
    • Neurofilament heavy polypeptide

    • NF-H

    • 200 kDa neurofilament protein

    • Neurofilament triplet H protein
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Immunocytochemistry

      • Immunohistochemistry
        View All» Product Name: Anti-Neurofilament 200kDa, clone NE14, Alexa Fluor® 555 Conjugate View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Format: AlexaFluor®555 View All» Host: Mouse View All»
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        © Merck Millipore代理MAB5256A5 Anti-Neurofilament 200kDa Antibody, clone NE14, Alexa Fluor® 555 Conjugate;抗-神经丝200kDa抗体，克隆NE14，Alex，产品报价联系微信jinshanbio