货号：04-447

品牌：Merck Millipore

规格：

目录价：￥5078.00

市场价格：￥4316.30

会员价格：￥4062.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-HSP27 Phospho (Ser78) Antibody, rabbit | 04-447 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: Recognizes a region composed of residues juxtaposed to Serine 78 of human HSP27. View All» Molecular Weight: 27 kDa View All» Immunogen: KLH-conjugated synthetic phosphor-peptide composed of residues juxtaposed to Serine 78 of human HSP27. View All» Modifications: Phosphorylation View All» Isotype: IgG View All» Species Reactivity: Human View All» Quality Assurance: Routinely evaluated by immunoblot. View All» Presentation: In 60% storage buffer (50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 0.01% sodium azide and 0.05% BSA) and 40% glycerol. View All» Storage Conditions: 2 year at -20°C from date of shipment. Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol-containing solutions to become frozen during storage. View All» UniProt Number: P04792 View All» Entrez Gene Number: NM_001540.2 View All» Gene Symbol:

• HSPB1

• Hs.76067

• HSP27

• Hsp25

• HspB1

• HSP28

• CMT2F

• HS.76067

• DKFZp586P1322

• HMN2B

• SRP27
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • Immunofluorescence

  • Immunoprecipitation

  • Western Blotting

  • Immunohistochemistry (Paraffin)
    View All» UniProt Summary: FUNCTION: SwissProt: P04792 # Involved in stress resistance and actin organization.SIZE: 205 amino acids; 22783 Da SUBUNIT: Interacts with TGFB1I1 (By similarity). Associates with alpha- and beta-tubulin and microtubules. Interacts with HSPB8 and HSPBAP1.SUBCELLULAR LOCATION: Cytoplasm. Nucleus. Note=Cytoplasmic in interphase cells. Colocalizes with mitotic spindles in mitotic cells. Translocates to the nucleus during heat shock.PTM: Phosphorylated in MCF-7 cells on exposure to protein kinase C activators and heat shock.DISEASE: SwissProt: P04792 # Defects in HSPB1 are the cause of Charcot-Marie-Tooth disease type 2F (CMT2F) [MIM:606595]. CMT2F is a form of Charcot- Marie-Tooth disease, the most common inherited disorder of the peripheral nervous system. Charcot-Marie-Tooth disease is classified in two main groups on the basis of electrophysiologic properties and histopathology: primary peripheral demyelinating neuropathy or CMT1, and primary peripheral axonal neuropathy or CMT2. Neuropathies of the CMT2 group are characterized by signs of axonal regeneration in the absence of obvious myelin alterations, normal or slightly reduced nerve conduction velocities, and progressive distal muscle weakness and atrophy. Nerve conduction velocities are normal or slightly reduced. CMT2F onset is between 15 and 25 years with muscle weakness and atrophy usually beginning in feet and legs (peroneal distribution). Upper limb involvement occurs later. CMT2F inheritance is autosomal dominant. & Defects in HSPB1 are a cause of distal hereditary motor neuropathy (dHMN) [MIM:608634]. Distal HMN is a pure motor peripheral neuropathy without sensory abnormalities.SIMILARITY: SwissProt: P04792 ## Belongs to the small heat shock protein (HSP20) family. View All» Brand Family: Upstate View All» Product Name: Anti-HSP27 Phospho (Ser78) Antibody, rabbit | 04-447 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Purified View All» Host: Rabbit View All»
    © 金山科研平台是专业的授权总代理区域代理经销平台。
    © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
    © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
    © 本文地址：https://www.16ao.com/thread-131857.htm
    © Merck Millipore代理04-447 Anti-HSP27 Phospho (Ser78)，产品报价联系微信jinshanbio