货号：04-449

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-MIP-1 β/CCL4 (C-term) Antibody | 04-449 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: Recognizes a region composed of residues at the C-terminus of human MIP-1 beta/CCL4. View All» Molecular Weight: 10 kDa View All» Immunogen: KLH-conjugated synthetic phosphor-peptide composed of residues at the C-terminus of human MIP-1 beta/CCL4. View All» Isotype: IgG View All» Species Reactivity: Human View All» Quality Assurance: Routinely evaluated by immunoblot. View All» Presentation: In 60% storage buffer (50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 0.01% sodium azide and 0.05% BSA) and 40% glycerol. View All» Storage Conditions: 2 year at -20°C from date of shipment. Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol-containing solutions to become frozen during storage. View All» UniProt Number: P13236 View All» Entrez Gene Number: NM_002984.2 View All» Gene Symbol:

• CCL4

• 1-69

• G-26

• LAG-1

• MGC126026

• ACT2

• Act-2

• HC21

• SCYA4

• SIS-gamma

• SCYA4L

• MGC104418

• H400

• ACT-2

• MGC126025

• LAG1

• MIP-1-beta

• MIP1B

• AT744.1

• SCYA2

• CCL4L
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» UniProt Summary: FUNCTION: SwissProt: P13236 # Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5- mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B.SIZE: 92 amino acids; 10212 Da SUBUNIT: Homodimer and heterodimer of MIP-1-alpha(4-69) and MIP-1- beta(3-69).SUBCELLULAR LOCATION: Secreted.PTM: N-terminal processed form MIP-1-beta(3-69) is produced by proteolytic cleavage after secretion from peripheral blood lymphocytes.SIMILARITY: SwissProt: P13236 ## Belongs to the intercrine beta (chemokine CC) family. View All» Brand Family: Upstate View All» Product Name: Anti-MIP-1 β/CCL4 (C-term) Antibody | 04-449 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Purified View All» Host: Rabbit View All»
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