货号：MAB5270-50UG

品牌：Merck Millipore

规格：50Ug

目录价：￥6127.00

市场价格：￥5207.95

会员价格：￥4901.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Choline Acetyltransferase Antibody, clone 1.B3.9B3 | MAB5270-50UG View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Reacts with choline acetyltransferase (ChAT)-positive cells from humans, rats and pigs (Ostermann-Fatif et al., 1992a,b). View All» Molecular Weight: 69 kDa View All» Immunogen: Highly purified ChAT obtained from porcine brain (Ostermann-Fatif et al., 1990). View All» Clone: 1.B3.9B3 View All» Isotype: IgG1 View All» Species Reactivity:

• Human

• Pig

• Rat
  View All» Application Notes: Western blot ELISA Immunohistochemistry: 10-20 μg/mL in paraffin embedded sections {See Ratcliffe et al. 1998} Optimal working dilutions and protocols must be determined by end user. View All» Control: Brain tissue View All» Purification Method: Protein A purfied View All» Presentation: Protein A Purified mouse immunoglobulin in PBS with 0.1% sodium azide as a preservative. View All» Storage Conditions: Maintain lyophilized antibody at 2–8°C in undiluted aliquots for up to 6 months. Maintain reconstituted antibody at -20°C in undiluted aliquots for up to 6 months. View All» UniProt Number: P28329 View All» Entrez Gene Number:
  • NM_020549.3

  • NM_020984.2

  • NM_020985.2

  • NM_020986.2
    View All» Gene Symbol:
    • CHAT

    • ChAT

    • CMS1A2

    • CHOACTase

    • CMS1A

    • EC 2.3.1.6
      View All» Alternate Names: ChAT View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • ELISA

      • Immunohistochemistry

      • Immunohistochemistry (Paraffin)

      • Western Blotting
        View All» Entrez Gene Summary: Cholinergic systems are implicated in numerous neurologic functions. Alteration in some cholinergic neurons may account for the disturbances of Alzheimer disease. The protein encoded by this gene synthesizes the neurotransmitter acetylcholine. Alternative splice variants have been found that contain alternative 5' untranslated exons. Three of the four described splice variants encode identical 69 kDa proteins while one variant encodes both the 69 kDa and a larger 82 kDa protein. View All» UniProt Summary: FUNCTION: SwissProt: P28329 # Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses.SIZE: 748 amino acids; 82568 Da DISEASE: SwissProt: P28329 # Defects in CHAT are the cause of familial infantile myasthenia gravis 2 (FIMG2) [MIM:254210, 254200]; also known as CMS-EA. FIMG2 patients have myasthenic symptoms since birth or early infancy, negative tests for anti-AChR antibodies, and abrupt episodic crises with increased weakness, bulbar paralysis, and apnea precipitated by undue exertion, fever, or excitement. Inheritance is autosomal recessive.SIMILARITY: SwissProt: P28329 ## Belongs to the carnitine/choline acetyltransferase family. View All» Brand Family: Chemicon View All» Product Name: Anti-Choline Acetyltransferase Antibody, clone 1.B3.9B3 | MAB5270-50UG View All» Concentration: 1 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 50 μg View All» Format: Purified View All» Host: Mouse View All»
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