货号：04-465

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-IL-1R1 Antibody, rabbit | 04-465 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: Recognizes a synthetic peptide encompassing residues near the N-terminus of human IL-1R type 1. View All» Molecular Weight: 80kDa View All» Immunogen: KLH-conjugated synthetic peptide encompassing residues near the N-terminus of human IL-1R type 1. View All» Isotype: IgG View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Quality Assurance: Routinely evaluated by immunoblot. View All» Presentation: 100 μL of rabbit monoclonal IgG in 60% storage buffer (50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 0.01% sodium azide and 0.05% BSA) and 40% glycerol. View All» Storage Conditions: 2 years at -20°C from date of shipment. Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol-containing solutions to become frozen during storage. View All» UniProt Number: P14778 View All» Entrez Gene Number: NM_000877.2 View All» Gene Symbol:
  • IL1R1

  • IL-1R-1

  • IL1R

  • P80

  • IL1RT1

  • IL1RA

  • IL-1R-alpha

  • CD121A

  • IL-1RT1

  • p80

  • D2S1473
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein is a receptor for interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA). It is an important mediator involved in many cytokine induced immune and inflammatory responses. This gene along with interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 2 (IL1RL2), and interleukin 1 receptor-like 1 (IL1RL1) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. View All» UniProt Summary: FUNCTION: SwissProt: P14778 # Receptor for interleukin-1 alpha (IL-1A), beta (IL-1B), and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappa-B. Signaling involves formation of a ternary complex containing IL1RAP, TOLLIP, MYD88, and IRAK1 or IRAK2.SIZE: 569 amino acids; 65402 Da SUBUNIT: Binds IL1RAP.SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.SIMILARITY: SwissProt: P14778 ## Belongs to the interleukin-1 receptor family. & Contains 3 Ig-like C2-type (immunoglobulin-like) domains. & Contains 1 TIR domain. View All» Brand Family: Upstate View All» Product Name: Anti-IL-1R1 Antibody, rabbit | 04-465 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Purified View All» Host: Rabbit View All»
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