货号：MAB5580

品牌：Merck Millipore

规格：100UL

目录价：￥5513.00

市场价格：￥4686.05

会员价格：￥4410.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Arrestin Antibody, visual | MAB5580 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Visual arrestin. The antibody has not been tested for reactivity to arrestin in other tissues. View All» Immunogen: Porcine visual arrestin. View All» Isotype: IgG1 View All» Background Information: Visual arrestin is a 48 kDa protein expressed exclusively in retinal photoreceptor cells where it regulates light-dependent signal transduction through G protein-coupled receptor (rhodopsin) activation. Visual arrestin is the major pathogenetic autoantigen in human autoimmume imflammatory eye disease. View All» Species Reactivity:

• Bovine

• Goat

• Human

• Pig

• Rat

• Sheep
  View All» Application Notes: Western blot: 48kDa Immunohistochemistry Immunopurification of arrestin Optimal working dilutions must be determined by end user. View All» Presentation: Ascites fluid. Liquid. View All» Storage Conditions: Maintain -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. View All» UniProt Number: P79260 View All» Gene Symbol:
  • ARR3

  • Arrestin-C

  • CAR

  • ARRX

  • C-arrestin

  • cArr
    View All» Alternate Names: S-antigen, rod arrestin View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunohistochemistry

    • Immunoprecipitation

    • Western Blotting
      View All» UniProt Summary: Function: Arrestin is one of the major proteins of the ros (retinal rod outer segments); it binds to photoactivated-phosphorylated rhodopsin, thereby apparently preventing the transducin-mediated activation of phosphodiesterase.Tissue specificity: Retina and pineal gland. Also expressed in the anterior tissues such as the ciliary epithelium and iris epithelium.Involvement in disease: S-antigen induces autoimmune uveitis.Miscellaneous: Arrestin binds calcium By similarity.Sequence similarities: Belongs to the arrestin family. View All» Brand Family: Chemicon View All» Product Name: Anti-Arrestin Antibody, visual | MAB5580 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Ascites View All» Host: Mouse View All»
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