货号：04-968

品牌：Merck Millipore

规格：

目录价：￥3853.00

市场价格：￥3275.05

会员价格：￥3082.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Folr4 (Folate receptor 4) Antibody, clone 5E12.2 | 04-968 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes Folate receptor 4 (Folr4). View All» Molecular Weight: ~26 kDa View All» Epitope: Unknown View All» Immunogen: KLH-conjugated linear peptide corresponding to human Folate receptor 4 (Folr4). View All» Clone: 5E12.2 View All» Isotype: IgG1κ View All» Background Information: Folates are necessary and critical components in the synthesis of proteins and nucleic acids, and have putative roles in the development of both the spinal canal and brain in the early stages of pregnancy (Yamaguchi, 2007). Folate receptor 4 (Folr4) is a recently discovered cell surface receptor for folic acid on T regulatory cells (Tregs). Studies have shown that Folr4 has an integral role in the maintenance of Treg cell function (Arase, 2009). Expression of Folr4 in Tregs is notably high, making it an opportune marker for the study of Treg cells. When studied in conjunction with CD4 and CD25, Folr4 also provides researchers with a marker to distinguish between Tregs and other T cells (Chai, 2008). Tregs are of interest in therapeutic, drug research due to their ability to actively suppress immune responses. View All» Species Reactivity:

• Human

• Mouse
  View All» Species Reactivity Note: Demonstrated to react with human and mouse. View All» Application Notes: Western Blot (SNAP ID) Analysis: 1 µg/mL of this antibody detected Folate receptor 4 (Folr4) in 10 µg of human thymus tissue lysate. View All» Control: Human thymus tissue lysate View All» Quality Assurance: Evaluated by Western Blot in human thymus tissue lysate.Western Blot Analysis: 0.5 µg/mL of this antibody detected Folate receptor 4 (Folr4) in 10 µg of human thymus tissue lysate.A previous lot was shown to detect Folate Receptor 4 in mouse thymus tissue lysate. View All» Purification Method: Protein G purfied View All» Presentation: Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: A6ND01 View All» Entrez Gene Number: NP_001073955.1 View All» Gene Symbol:
  • Folbp3

  • Folr4

  • FR-delta
    View All» Alternate Names:
    • folate receptor 4 (delta) homolog (mouse)

    • folate receptor 4 (delta) homolog

    • Folate receptor 4
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» UniProt Summary: SUBCELLULAR LOCATION: Secreted Potential. PTM: Eight disulfide bonds are present Potential.SEQUENCE SIMILARITIES: Belongs to the folate receptor family. View All» Product Name: Anti-Folr4 (Folate receptor 4), clone 5E12.2 View All» Concentration: 1.0 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Mouse View All»
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