货号：05-1000X

品牌：Merck Millipore

规格：50Ug

目录价：￥4131.00

市场价格：￥3511.35

会员价格：￥3304.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Phosphoserine Antibody, clone 4A4 | 05-1000X View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: Serine-phosphorylated proteins from all species View All» Molecular Weight: Dependent upon the molecular weight of the serine phosphorylated protein being detected. View All» Immunogen: Phosphoserine coupled to KLH View All» Modifications: Phosphorylation View All» Clone: 4A4 View All» Isotype: IgG1 View All» Background Information: The identification of protein phosphorylation as a regulatory mechanism originated from studies by Fischer and Krebs in the mid 1950s that later earned them the 1992 Nobel prize. It is the major mechanism for the regulation of diverse cellular processes including cell division, protein synthesis, transcriptional regulation and neurotransmission. The steady state phosphorylation of any given substrate is governed by the opposing activities of kinases and phosphatases. It is now believed that a third of all eukaryotic cellular proteins are phosphorylated and that the majority of all phosphorylation events occur on serine and threonine residues (greater than 95%). View All» Species Reactivity: Vertebrates View All» Control: Suggested Positive Control: Cat.# 12-628, Calyculin A/Okadaic-treated A431 cell lysate is recommended as a positive control for western immunoblotting. Aliquot as desired, refreeze immediately, and store at –20ºC. The lysate is stable for 6 months at –20ºC. View All» Quality Assurance: Routinely evaluated by immunoblot analysis on lysate from Calyculin A/Okadaic-treated human A431 carcinoma cells. View All» Purification Method: Protein G-Sepharose™ chromatography View All» Presentation: 50 µL of PBS with 0.05% sodium azide with 30% glycerol. View All» Storage Conditions: 2 years at -20°C from date of shipment. For maximum recovery of the product, centrifuge the original vial prior to removing the cap. If the product has accidentally been frozen and thawed, spin it at 13,000 x g for 10 minutes at 2-8°C. View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:

• Western Blotting

• Immunofluorescence

• Flow Cytometry

• Immunohistochemistry (Paraffin)

• ELISA
  View All» Brand Family: Upstate View All» Product Name: Anti-Phosphoserine, clone 4A4 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 50 μg View All» Format: Purified View All» Host: Mouse View All»
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