货号：05-1066

品牌：Merck Millipore

规格：100Ug

目录价：￥5053.00

市场价格：￥4295.05

会员价格：￥4042.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Insulin Antibody, clone E11D7 | 05-1066 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: Recognizes insulin View All» Molecular Weight: 6 kDa View All» Epitope: Insulin View All» Immunogen: Human recombinant Insulin View All» Clone: E11D7 View All» Isotype: IgG1κ View All» Background Information: Insulin is a polypeptide hormone that regulates carbohydrate metabolism. Apart from being the primary agent in carbohydrate homeostasis, it has effects on fat metabolism. View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Species Reactivity Note: Human tested. Not tested with other species, but expected to react with Mouse and Rat based on sequence homology. View All» Application Notes: ELISA (Direct) Analysis:Insulin-coated plate was incubated with Anti-Insulin, clone E11D7 in 2-fold serial dilutions diluted in PBST from 5 μg/mL to 0.01 μg/mL. View All» Quality Assurance: Immunohistochemistry Analysis:20 μg/mL of this antibody detected insulin in β cells. View All» Purification Method: Protein G purfied View All» Presentation: Purified mouse monolconal IgG1κ in 0.1M Tris-Glycine (pH7.4), 150mM NaCl with 0.05%NaN3 View All» Storage Conditions: Stable for 1 year at 2-8ºC from date of receipt. View All» UniProt Number: P01308 View All» Entrez Gene Number: NM_000207.2 View All» Gene Symbol:
  • INS

  • proinsulin

  • insulin
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • ELISA

    • Immunohistochemistry (Paraffin)
      View All» Entrez Gene Summary: After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] View All» UniProt Summary: FUNCTION: SwissProt: P01308 # Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.SIZE: 110 amino acids; 11981 Da SUBUNIT: Heterodimer of a B chain and an A chain linked by two disulfide bonds.SUBCELLULAR LOCATION: Secreted.DISEASE:SwissProt: P01308 # Defects in INS are the cause of familial hyperproinsulinemia [MIM:176730].SIMILARITY: SwissProt: P01308 ## Belongs to the insulin family. View All» Product Name: Anti-Insulin Antibody, clone E11D7 | 05-1066 View All» Concentration: 1 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Mouse View All»
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