货号：05-1108

品牌：Merck Millipore

规格：1mg

目录价：￥5207.00

市场价格：￥4425.95

会员价格：￥4165.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Insulin Antibody, clone1 | 05-1108 View All» Replaces: CBL71 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes an epitope including the amino acid B30. View All» Molecular Weight: Approx. 12 kDa View All» Immunogen: Biosynthetic human insulin View All» Clone: MAB1 View All» Isotype: IgG1 View All» Background Information: Insulin is a polypeptide hormone that regulates carbohydrate metabolism. Apart from being the primary agent in carbohydrate homeostasis, it has effects on fat metabolism. View All» Species Reactivity: Human View All» Species Reactivity Note: Human View All» Control: Human pancreas tissue. View All» Quality Assurance: Evaluated by Immunohistochemistry in human pancreas tissue.Immunohistochemistry Analysis: 1.25 µg/mL of this antibody detected insulin in human pancreas tissue. View All» Purification Method: Affinity Purfied View All» Presentation: The monoclonal is presented as 1mg in 1ml phosphate buffered saline containing 10mM sodium azide. We recommend that each laboratory determine an optimum working titre for use in its particular application. View All» Storage Conditions: Store at 2-8°C and use within 1 year from date of receipt. View All» UniProt Number: P01308 View All» Entrez Gene Number: P01308 View All» Gene Symbol:

• ILPR

• IRDN

• OTTHUMP00000011161

• OTTHUMP00000011162

• OTTHUMP00000196038

• insulin

• proinsulin
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Immunohistochemistry (Paraffin) View All» UniProt Summary: FUNCTION: Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.SUBUNIT STRUCTURE: Heterodimer of a B chain and an A chain linked by two disulfide bonds.SUBCELLULAR LOCATION: Secreted. INVOLVEMENT IN DISEASE: Defects in INS are the cause of familial hyperproinsulinemia [MIM:176730].PHARMACEUTICAL USE: Available under the names Humulin or Humalog (Eli Lilly) and Novolin (Novo Nordisk). Used in the treatment of diabetes. Humalog is an insulin analog with 52-Lys-Pro-53 instead of 52-Pro-Lys-53.SEQUENCE SIMILARITIES: Belongs to the insulin family.SEQUENCE CAUTION: The sequence AAA59179.1 differs from that shown. Reason: Erroneous gene model prediction. View All» Product Name: Anti-Insulin, clone MAB1 View All» Concentration: 1 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 1 mg View All» Format: Affinity Purified View All» Host: Mouse View All»
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