货号：05-1563

品牌：Merck Millipore

规格：

目录价：￥3346.00

市场价格：￥2844.10

会员价格：￥2676.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-PI3-kinase type 3 Antibody, clone 17D1.1 | 05-1563 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~110 kDa observed View All» Immunogen: KLH-conjugated linear peptide corresponding to human PI3-kinase type 3. View All» Clone: 17D1.1 View All» Isotype: IgMκ View All» Background Information: PI3-kinase type 3 (also known as VPS34 or PIK3C3) is a member of the phosphatidylinositide 3-kinase family and plays a role in phosphoinositide lipid metabolism. PI3-kinase type 3 may be important in the pathogenesis of schizophrenia. PI3-kinase type 3 has also been found to regulate many different portions in the endosomal and autophagic pathways. A PI3-kinase type 3 deficiency has shown severe failing in cell proliferation and embryogenesis, missing the mesoderm development. View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Species Reactivity Note: Demonstrated to react with Human, Mouse, and Rat. View All» Control: NIH3T3 cell lysate View All» Quality Assurance: Evaluated by Western Blot in NIH3T3 cell lysate.Western Blot Analysis: 1 µg/mL of this antibody detected PI3-kinase type 3 on 10 µg of NIH3T3 cell lysate. View All» Purification Method: Affinity purified View All» Presentation: Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q8NEB9 View All» Entrez Gene Number: NP_002638 View All» Gene Symbol:
  • PIK3C3

  • VPS34
    View All» Alternate Names:
    • Phosphatidylinositol 3-kinase catalytic subunit type 3

    • PI3-kinase type 3

    • PI3K type 3

    • PtdIns-3-kinase type 3

    • Phosphatidylinositol 3-kinase p100 subunit

    • Phosphoinositide-3-kinase class 3

    • hVps34
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Immunocytochemistry
        View All» UniProt Summary: FUNCTION: Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis.CATALYTIC ACTIVITY: ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 3-phosphate.COFACTOR: Manganese.SUBUNIT STRUCTURE: Heterodimer. This subunit, part of a complex composed of regulatory and catalytic subunits, associates with regulatory subunit PIK3R4. Forms a complex with BECN1, PIK3R4 and either UVRAG and KIAA0226/Rubicon, or with ATG14. In this complex, presence of UVRAG and ATG14 are mutually exclusive.SUBCELLULAR LOCATION: Midbody.TISSUE SPECIFICITY: Ubiquitously expressed, with a highest expression in skeletal muscle.SEQUENCE SIMILARITIES: Belongs to the PI3/PI4-kinase family. Contains 1 PI3K/PI4K domain. View All» Product Name: Anti-PI3-kinase type 3, clone 17D1.1 View All» Concentration: 1 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Mouse View All»
        © 金山科研平台是专业的授权总代理区域代理经销平台。
        © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
        © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
        © 本文地址：https://www.16ao.com/thread-132649.htm
        © Merck Millipore代理05-1563 Anti-PI3-kinase type 3, clone 17D1.1 (mouse monoclonal)，产品报价联系微信jinshanbio