货号：MABC137

品牌：Merck Millipore

规格：

目录价：￥4118.00

市场价格：￥3500.30

会员价格：￥3294.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-ATG5 Antibody, clone EPR1755(2), Rabbit | MABC137 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~55 kDa observed. The long isoform can be observed at ~32 kDa in some lysates. View All» Immunogen: Synthetic peptide corresponding to human ATG5. View All» Clone: EPR1755(2) View All» Isotype: IgG View All» Background Information: Atg5 (Autophagy protein 5) is required for autophagy. It conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed. Atg5 may also play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity (1). View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Species Reactivity Note: Demonstrated to react with human, mouse, and rat. View All» Application Notes: Immunocytochemistry Analysis: A 1:100-250 dilution from a representative lot was used in IC. Immunoprecipitation Analysis: A 1:10 dilution from a representative lot data was used in IP.Immunohistochemistry Analysis: A 1:100-250 dilution from a representative lot detected ATG5 in human hepatocellular carcinoma tissue. View All» Control: Raji, HeLa, HT-1080, fetal kidney, C6, Raw264.7, PC-12, and NIH/3T3 cell lysates View All» Quality Assurance: Evaluated by Western Blot in Raji, HeLa, HT-1080, fetal kidney, C6, Raw264.7, PC-12, and NIH/3T3 cell lysates.Western Blot Analysis: A 1:1,000-10,000 dilution of this antibody detected ATG5 in Raji, HeLa, HT-1080, fetal kidney, C6, Raw264.7, PC-12, and NIH/3T3 cell lysates. View All» Purification Method: Unpurified View All» Presentation: Rabbit Monoclonal in buffer containing 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl containing 40% Glycerol, 0.01% sodium azide and 0.05% BSA. View All» Storage Conditions: Stable for 1 year at -20ºC from date of receipt. Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage. View All» UniProt Number: Q9H1Y0 View All» Gene Symbol:
  • ASP

  • APG5L

  • APG5

  • hAPG5
    View All» Alternate Names:
    • ATG5 autophagy related 5 homolog (S. cerevisiae)

    • APG5 (autophagy 5, S. cerevisiae)-like

    • Apoptosis-specific protein

    • APG5 autophagy 5-like (S. cerevisiae)

    • ATG5 autophagy related 5-like

    • autophagy protein 5

    • APG5-LIKE2

    • APG5 autophagy 5-like

    • apoptosis specific protein

    • APG5-like
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Immunohistochemistry (Paraffin)

      • Immunoprecipitation

      • Immunocytochemistry
        View All» Product Name: Anti-ATG5, clone EPR1755(2), Rabbit Monoclonal View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Diluted Culture Supernatant View All» Host: Rabbit View All»
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