货号:MABC72
品牌:Merck Millipore
规格:
目录价:¥4439.00
市场价格:¥3773.15
会员价格:¥3551.20
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Description:
Anti-TNF receptor-associated factor 1 (TRAF1) Antibody, clone 11B2.2 | MABC72
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Promotional Text:
Special Shipping Offer on Antibodies100% Performance Guaranteed
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Molecular Weight:
~46 kDa observed
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Immunogen:
GST-tagged recombinant protein corresponding to human TNF receptor-associated factor 1.
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Clone:
11B2.2
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Isotype:
IgG1κ
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Background Information:
TNF receptor-associated factor 1 is an adapter protein belonging to the TRAF family. It contains the conserved C-terminal TRAF domain that is required for trimerization and interaction with cell surface receptors such as CD30, CD40, OX40, AITR, and RANK. TNF receptor-associated factor 1 also interacts with a variety of cytoplasmic proteins such as RIP1, RIP2, A20 and TRIP. Among other functions, TNF receptor-associated factor 1 is involved in regulating NF-kB and JNK signaling. TNF receptor-associated factor 1 is expressed in the lung, testis, and spleen, and can be induced by TNF-α, interleukin (IL)-1 or EBV infection. Previous studies have suggested that TNF receptor-associated factor 1 may play a role in oncogenesis.
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Species Reactivity:
Human
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Species Reactivity Note:
Demonstrated to react with Human.
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Control:
Raji cell lysate
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Quality Assurance:
Evaluated by Western Blot in Raji cell lysate.Western Blot Analysis: 1 µg/mL of this antibody detected TNF receptor-associated factor 1 on 10 µg of Raji cell lysate.
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Purification Method:
Protein G purified
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Presentation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
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Storage Conditions:
Stable for 1 year at 2-8°C from date of receipt.
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UniProt Number:
Q13077
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Entrez Gene Number:
NP_001177874
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Gene Symbol:
-
TRAF1
-
EBI6
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Alternate Names:
-
TNF receptor-associated factor 1
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Epstein-Barr virus-induced protein 6
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Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Western Blotting
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Product Name:
Anti-TNF receptor-associated factor 1 (TRAF1), clone 11B2.2
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Concentration:
1 mg/mL
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Antibody Type:
Monoclonal Antibody
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Qty/Pk:
100 μg
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Format:
Purified
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Host:
Mouse
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