货号：MABC76

品牌：Merck Millipore

规格：100Ug

目录价：￥4931.00

市场价格：￥4191.35

会员价格：￥3944.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Stabilin-2 Antibody, clone mAb-174 | MABC76 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~190 kDa observed. The calculated molecular weight of this protein is 155 kDa, but can be observed at ~190 kDa due to high glycosylation. An uncharacterized band appears at ~20 kDa in some lysates. View All» Immunogen: Partially purified rat Stabilin-2 from the HA binding region. View All» Clone: mAb-174 View All» Isotype: IgG1κ View All» Background Information: Stabilin-2 (Stab2; FEEL-2; and HARE) is a phosphatidylserine receptor that is localized to hepatic sinusoidal endothelial cells. It is a large protein containing a linker domain, two laminin EGF-like domains, four FAS1 domains, and six EGF-like domains, enabling stabilin-2 to perform multiple functions. Stabilin-2 is primarily studied for its role as a scavenger receptor that is involved in the clearance of metabolic waste products, which may include hyaluronic acid, heparin, advanced glycation end-products, acetylated LDL, and chondroitin sulfates. Previous studies have also suggested that stabilin-2 may play a role in cell adhesion processes. View All» Species Reactivity: Rat View All» Species Reactivity Note: Demonstrated to react with Rat. View All» Application Notes: Immunohistochemistry Analysis: A representative lot was used by an independent laboratory in spleen, liver, and lymph node tissues. (Weigel, P., et al. (2003). Journal of Biological Chemistry. 278(11):9808–9812.) View All» Control: Rat spleen tissue lysate View All» Quality Assurance: Evaluated by Western Blot in rat spleen tissue lysate.Western Blot Analysis: 2 µg/mL of this antibody detected Stabilin-2 on 10 µg of rat spleen tissue lysate. View All» Purification Method: Protein G purified View All» Presentation: Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q8CFM6 View All» Gene Symbol:

• Stab2

• Feel2

• Hare
  View All» Alternate Names:
  • Stabilin-2

  • Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 2

  • FEEL-2

  • Hyaluronan receptor for endocytosis

  • 175 kDa stabilin-2

  • 175 kDa hyaluronan receptor for endocytosis
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Western Blotting

    • Immunohistochemistry
      View All» Product Name: Anti-Stabilin-2, clone mAb-174 View All» Concentration: 1 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Mouse View All»
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