货号:MABC95
品牌:Merck Millipore
规格:100Ug
目录价:¥5666.00
市场价格:¥4816.10
会员价格:¥4532.80
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Description:
Anti-S1PR2/EDG5 Antibody, clone 6E8.1 | MABC95
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Promotional Text:
Special Shipping Offer on Antibodies100% Performance Guaranteed
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Specificity:
This antibody recognizes the cytoplasmic domain of S1PR2/EDG5.
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Molecular Weight:
~35 kDa observed
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Epitope:
Cytoplasmic domain
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Immunogen:
GST-tagged recombinant protein corresponding to the cytoplasmic domain of human S1PR2/EDG5.
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Clone:
6E8.1
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Isotype:
IgMκ
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Background Information:
Sphingosine 1-phosphate receptor 2 (S1PR2), otherwise known as EDG5, is a ubiquitous G-protein coupled receptor for lysosphingolipid sphingosine 1-phosphate (S1P). It is coupled to Gi, G12/13, and Gq pathways to regulate a number of second messengers and effector molecules, including cAMP, PLC, MAPK, RhoA, and Rac. S1PR2 mediates the effects of S1P on cell motility and embryonic development, among other cellular processes.
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Species Reactivity:
Human
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Species Reactivity Note:
Demonstrated to react with Human.
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Application Notes:
Immunohistochemistry Analysis: A representative lot detected S1PR2/EDG5 in human tonsil, liver, colorectal cancer tissues.
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Control:
Human liver tissue lysate
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Quality Assurance:
Evaluated by Western Blot in human liver tissue lysate.Western Blot Analysis: 1 mg/mL of this antibody detected S1PR2/EDG5 in 10 mg of human liver tissue lysate.
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Purification Method:
Purified by ion-exchange chromatography
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Presentation:
Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.
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Storage Conditions:
Stable for 1 year at 2-8°C from date of receipt.
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UniProt Number:
O95136
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Entrez Gene Number:
NP_004221
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Gene Symbol:
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S1PR2
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EDG5
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Alternate Names:
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Sphingosine 1-phosphate receptor 2
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S1P receptor 2
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S1P2
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Endothelial differentiation G-protein coupled receptor 5
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Sphingosine 1-phosphate receptor Edg-5
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S1P receptor Edg-5
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Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
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Western Blotting
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Immunohistochemistry (Paraffin)
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Product Name:
Anti-S1PR2/EDG5, clone 6E8.1
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Concentration:
0.5 mg/mL
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Antibody Type:
Monoclonal Antibody
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Qty/Pk:
100 μg
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Format:
Purified
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Host:
Mouse
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