货号:MABC97
品牌:Merck Millipore
规格:100Ug
目录价:¥5513.00
市场价格:¥4686.05
会员价格:¥4410.40
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Description:
Anti-S1PR4/EDG6 Antibody, clone 16B9.1 | MABC97
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Promotional Text:
Special Shipping Offer on Antibodies100% Performance Guaranteed
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Molecular Weight:
~42 kDa observed
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Immunogen:
GST-tagged recombinant protein corresponding to human S1PR4/EDG6.
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Clone:
16B9.1
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Isotype:
IgMκ
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Background Information:
Sphingosine 1-phosphate receptor 4 (S1PR4), otherwise known as EDG6, is present, in varying expression levels, in the adult lymph node, bone marrow, and thymus, as well as fetal liver, lung, and thymus. It is activated by the lysosphingolipid sphingosine 1-phosphate, and is coupled to Gi and G12/13 G proteins and via their various effector molecules, SIP4 regulates cell proliferation, differentiation, motility, and migration.
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Species Reactivity:
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Human
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Rat
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Application Notes:
Immunohistochemistry Analysis: A 1:300 dilution from a representative lot detected S1PR4/EDG6 in human red bone marrow and human tonsil tissues.
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Control:
Rat spleen tissue lysate
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Quality Assurance:
Evaluated by Western Blot Analysis in rat spleen tissue lysate.Western Blot Analysis: 1 µg/mL of this antibody detected S1PR4/EDG6 in 10 µg of rat spleen tissue lysate.
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Purification Method:
Purified by ion-exchange chromatography
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Presentation:
Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.
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Storage Conditions:
Stable for 1 year at 2-8°C from date of receipt.
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UniProt Number:
O95977
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Entrez Gene Number:
NP_003766
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Gene Symbol:
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S1PR4
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EDG6
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Alternate Names:
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Sphingosine 1-phosphate receptor 4
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S1P receptor 4
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S1P4
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Endothelial differentiation G-protein coupled receptor 6
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Sphingosine 1-phosphate receptor Edg-6
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S1P receptor Edg-6
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Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
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Western Blotting
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Immunohistochemistry
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Product Name:
Anti-S1PR4/EDG6, clone 16B9.1
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Concentration:
0.5 mg/mL
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Antibody Type:
Monoclonal Antibody
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Qty/Pk:
100 μg
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Format:
Purified
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Host:
Mouse
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