货号：MABD70

品牌：Merck Millipore

规格：

目录价：￥3908.00

市场价格：￥3321.80

会员价格：￥3126.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Novel hES cell marker CC9 Antibody, clone CC9-D6-D5 | MABD70 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody exhibits high reactivity to both human embryonic stem (ES) cells and embryonal carcinoma (EC) cells similar to SSEA3 and TRA-1-60 (Wright, A., et al. (2011). Int J Androl. 34(4 Pt 2):e175-e187). View All» Molecular Weight: Novel hES cell marker clone CC9 recognizes diffuse bands by western blot at ~200-250 kDa. The peptipe bound by this antibody may contain a cell surface carohydrate residue (Wright, A., et al. (2011). Int J Androl. 34(4 Pt 2):e175-e187). View All» Epitope: 0 View All» Immunogen: Shef-1 human embryonic stem cells View All» Clone: CC9-D6-D5 View All» Isotype: IgMκ View All» Background Information: Stem cells are unspecialized cells capable of renewing themselves through cell division and can differentiate into diverse specialized cell types. Embryonic stem cells, as the name suggests, are derived from embryos. Stem cell markers refer to the cell surface receptors that selectively bind signaling molecules. Each cell type has a unique combination of receptors on their surface that makes each cell type distinguishable from other kinds of cells. Novel hES cell marker CC9 binds a panel of ES and EC cells with a marked reduction in binding to NTERA-2 cells upon retinoic acid-induced differentiation. The epitope bound by this MAb is likely to be a cell surface carbohydrate residue, as treatment of 2102Ep with neuraminidase markedly reduces antibody binding. In cell staining this MAb shows differential staining between undifferentiated and differentiated regions of cells within the hESC culture, although at high concentrations some background staining on matrigel and fibroblast feeders is observed. View All» Species Reactivity: Human View All» Species Reactivity Note: Demonstrated to react with Human. View All» Application Notes: Flow Cytometry Analysis: A representative lot was used by an independent laboratory to analyze human embryonic stem cells and embryonic carcinoma cells (Wright, A., et al. (2011). Int J Androl. 34(4 Pt 2):e175-e187).Immunohistochemistry Analysis: A representative lot was used by an independent laboratory in human testicular germ cell tumors (Wright, A., et al. (2011). Int J Androl. 34(4 Pt 2):e175-e187).Western Blot Analysis: A representative lot was used by an independent laboratory in n2102Ep cell lysate (Wright, A., et al. (2011). Int J Androl. 34(4 Pt 2):e175-e187). View All» Control: H9 Human embryonic stem cells View All» Quality Assurance: Evaluated by Immunocytochemistry in H9 human embryonic stem cells.Immunocytochemistry Analysis: A 1:500 dilution of this antibody stained the cytosol of H9 human embryonic stem cells. View All» Purification Method: Purified by ion exchange chromatography View All» Presentation: Purified mouse monoclonal IgMκ in PBS with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:

• Immunocytochemistry

• Flow Cytometry

• Immunohistochemistry

• Western Blotting
  View All» Product Name: Anti-Novel hES cell marker CC9, clone CC9-D6-D5 View All» Concentration: 0.25 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Mouse View All»
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