货号：MABE192

品牌：Merck Millipore

规格：

目录价：￥3364.00

市场价格：￥2859.40

会员价格：￥2691.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-hnRNP-P2 Antibody, clone LHC7.15 | MABE192 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~65 kDa observed View All» Immunogen: Mouse spleen fused with SP2 cells View All» Clone: LHC7.15 View All» Isotype: IgG2aκ View All» Background Information: hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA) which are involved in pre-mRNA processing and other aspects of mRNA metabolism. Proteins of the heterogeneous nuclear ribonucleoparticles (hnRNP) family form a structurally diverse group of RNA binding proteins implicated in various functions. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. Studies have indicated that hnRNP P2 may play a role in genomic integrity. View All» Species Reactivity: Mouse View All» Species Reactivity Note: Demonstrated to react with Mouse. View All» Application Notes: Immunocytochemistry Analysis: A previous lot was used by an independent laboratory in Jurkat cells. (Radic, M., et al. (2006). The Journal of Immunology. 176: 68–74.)Western Blot Analysis: A previous lot was used by an independent laboratory in cellular extracts of live and apoptotic Jurkat cells. (Radic, M., et al. (2006). The Journal of Immunology. 176: 68–74.) View All» Control: NIH/3T3 nuclear extract View All» Quality Assurance: Evaluated by Western Blot in NIH/3T3 nuclear extract.Western Blot Analysis: 0.5 µg/mL of this antibody detected hnRNP-P2 on 10 µg of NIH/3T3 nuclear extract. View All» Purification Method: Protein G purified View All» Presentation: Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: P56959 View All» Entrez Gene Number: NP_631888 View All» Gene Symbol: Fus View All» Alternate Names:

• RNA-binding protein FUS

• Protein pigpen

• hnRNP-P2

• hnRNP P2
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • Western Blotting

  • Immunocytochemistry
    View All» UniProt Summary: FUNCTION: Binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single-stranded DNAs and D-loop formation in superhelical double-stranded DNA. May play a role in maintenance of genomic integrity (By similarity).SUBUNIT STRUCTURE: Component of nuclear riboprotein complexes. Interacts with ILF3, TDRD3 and SF1. Interacts with OTUB1 and SARNP (By similarity).SUBCELLULAR LOCATION: Nucleus (By similarity). SEQUENCE SIMILARITIES: Belongs to the RRM TET family.Contains 1 RanBP2-type zinc finger.Contains 1 RRM (RNA recognition motif) domain. View All» Product Name: Anti-hnRNP-P2, clone LHC7.15 View All» Concentration: 0.25 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 200 µL View All» Format: Purified View All» Host: Mouse View All»
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