Merck Millipore代理MABE339 Anti-p53 (wild type) Antibody, clone PAb1620;抗-p53(野生型)抗体,克隆PAb1620store at +2℃ to +8℃

2025-06-27

货号:MABE339

品牌:Merck Millipore

规格:100Ug

目录价:¥5053.00

市场价格:¥4295.05

会员价格:¥4042.40

金山科研平台,产品价格货期咨询微信:jinshanbio Description: Anti-p53 (wild type) Antibody, clone PAb1620 | MABE339 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~53 kDa observed View All» Immunogen: Mouse VLM tumor cells. View All» Clone: Pab1620 View All» Isotype: IgG2aκ View All» Background Information: Wild-type p53 is present in the nucleus of all normal mammalian cells where it appears to be involved in the regulation of cell proliferation. The normal protein has a very short half-life and is present in only minute amounts in normal tissues and cells. In contrast, mutant p53 protein produced by malignant cells is usually a product of a point mutation in the p53 gene leading to substitution of a single amino acid that significantly prolongs the half-life of the protein. The accumulation of high levels of p53 is a potential novel marker for malignancy. View All» Species Reactivity:

  • Human

  • Mouse

    View All» Species Reactivity Note: Demonstrated to react with Mouse and Human. View All» Application Notes: Immunohistochemistry Analysis: A 1:50 dilution of this antibody detected p53 in normal human brain tissue.Immunoprecipitation Analysis: A representative lot from an independent laboratory detected p53 in IP (Lu, X., et al. (1992). Cell. 70(1):153-161.).Immunohistochemistry Analysis: A representative lot from an independent laboratory detected p53 in dorsal skin samples from animal trunks (Kramata, P., et al. (2005). Cancer Res. 65(9):3577-3585.) and in certain human cancer tissues (Cordon-Cardo, C., et al, (1991). 51(23 Pt 1):6372-6380.). View All» Control: Mouse brain tissue lysate View All» Quality Assurance: Evaluated by Western Blot in mouse brain tissue lysate.Western Blot Analysis: 1 µg/mL of this antibody detected p53 in mouse brain tissue lysate. View All» Purification Method: Protein G purified View All» Presentation: Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: P02340 View All» Entrez Gene Number: NP_001120705 View All» Gene Symbol:
    • Tp53

    • P53

    • Trp53

      View All» Alternate Names:
      • Cellular tumor antigen p53

      • Tumor suppressor p53

        View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
        • Western Blotting

        • Immunohistochemistry

          View All» Product Name: Anti-p53 (wild type), clone PAb1620 View All» Concentration: 1 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Mouse View All»

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