货号：MABE366

品牌：Merck Millipore

规格：100Ug

目录价：￥5359.00

市场价格：￥4555.15

会员价格：￥4287.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-SNF2L Antibody, clone SNF 2C4 | Cat. No. MABE366 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~121 and ~123 kDa observed. Uniprot describes 5 tyrosine phosphorylation sites. View All» Immunogen: GST-tagged recombinant protein corresponding to human SNF2L. View All» Clone: SNF 2C4 View All» Isotype: IgG2bκ View All» Background Information: Nucleosome-remodeling factor subunit SNF2L, also known as SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1 (SMARCA1), is the energy-transducing component of NURF (nucleosome-remodeling factor) and CERF (CECR2-containing-remodeling factor) complexes. These complexes facilitate the disruption of chromatin structure in an ATP-dependent manner. SNF2L potentiates neurite outgrowth, and may be involved in brain development by regulating En-1 and En-2 expression as well as in the development of luteal cells. View All» Species Reactivity: Human View All» Species Reactivity Note: Demonstrated to react with Human. View All» Application Notes: Western Blot Analysis: A representative lot was used by an an independent laboratory to detect SNF2L in untransfected HeLa whole cell extracts, but demonstrated a loss of signal in HeLa whole cell extracts transfected with siRNA. (Eckey, M., et al. (2012). Mol Cell Biol. 32(13):2359-2371).Immunohistochemistry Analysis: A representative lot was used by an an independent laboratory to detect SNF2L in certain, normal human organ tissues. (Eckey, M., et al. (2012). Mol Cell Biol. 32(13):2359-2371). View All» Control: HeLa cell lysate View All» Quality Assurance: Evaluated by Western Blot in HeLa cell lysate.Western Blot Analysis: 1.0 µg/mL of this antibody detected SNF2L in 10 µg of HeLa cell lysate. View All» Purification Method: Protein G purified View All» Presentation: Purified rat monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: P28370 View All» Entrez Gene Number: NP_003060 View All» Gene Symbol:

• SMARCA1

• SNF2L

• SNF2L1
  View All» Alternate Names:
  • Probable global transcription activator SNF2L1

  • ATP-dependent helicase SMARCA1

  • Nucleosome-remodeling factor subunit SNF2L

  • SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Western Blotting

    • Immunohistochemistry
      View All» Product Name: Anti-SNF2L, clone SNF 2C4 View All» Concentration: 1 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Rat View All»
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