货号：MABF122

品牌：Merck Millipore

规格：

目录价：￥3574.00

市场价格：￥3037.90

会员价格：￥2859.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-TLR6, clone 7H2.1 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: 92 kDa calculated View All» Immunogen: KLH-conjugated linear peptide corresponding to human TLR6. View All» Clone: 7H2.1 View All» Isotype: IgMκ View All» Background Information: Toll-like receptor 6 (TLR6) is a transmembrane protein that has been detected on plasmacytoid pre-dendritic cells, dermal microvessel endothelial cells, and CD11c+ dendritic cells. As a member of the toll-like receptor family, it contains multiple leucine rich repeats in the extracellular domain and a IL1 receptor motif in the cytoplasmic domain. TLR6 is a pattern-recognition receptor that recognizes pathogen-associated molecular patterns (PAMPs) on microbial agents. It recognizes mycoplasmal macrophage-activating lipopeptide (MALP-2); soluble tuberculosis factor (STF); phenol-soluble modulin (PSM); and B. burgdorferi outer surface protein A lipoprotein (OspA-L). TLR6 interacts with the MYD88 adaptor protein to activate NF-kappa B signaling pathway leading to the secretion of cytokines and the induction of inflammatory responses. View All» Species Reactivity: Human View All» Species Reactivity Note: Demonstrated to react with Human. View All» Application Notes: Western Blot Analysis: 2.5 µg/mL from a representative lot detected TLR6 in 10 µg of TLR6 overexpression lysate.Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected TLR6 in human tonsil tissue. View All» Control: Human PBMC's View All» Quality Assurance: Evaluated by Flow Cytometry in human PBMC's.Flow Cytometry Analysis: 0.5 µg of this antibody detected TLR6 in human PBMC's. View All» Purification Method: Purified by ion-exchange chromatography View All» Presentation: Purified mouse monoclonal IgMκ in PBS containing 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q9Y2C9 View All» Entrez Gene Number: NP_006059 View All» Gene Symbol: TLR6 View All» Alternate Names:

• Toll-like receptor 6

• CD286
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • Flow Cytometry

  • Immunohistochemistry (Paraffin)

  • Western Blotting
    View All» Product Name: Anti-TLR6, clone 7H2.1 View All» Concentration: 0.5 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Mouse View All»
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