货号：MABF37

品牌：Merck Millipore

规格：

目录价：￥3724.00

市场价格：￥3165.40

会员价格：￥2979.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-CD24 Antibody, clone M1/69 | MABF37 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~ 30 kDa observed View All» Immunogen: Whole B10 spleen cells View All» Isotype: IgG2bκ View All» Background Information: The CD24 antigen (also known as Small cell lung carcinoma cluster 4 antigen), which has a molecular weight of 35-45 kDa, is a glycosyl phosphatidylinositol (GPI)-anchored surface molecule. It is a member of a family that also includes HSA and CD52. Cross-linking of CD24 can induce increased intracellular Ca++ in mature B lymphocytes (Turni, 2002).CD24 is expressed at multiple stages of B cell development, beginning with the bone marrow CD34+ pro-B-cell compartment and continuing through mature surface IgM+/IgD+ B cells. Plasma cells express very low to negligible levels of CD24 (Le Bien, 1995). CD24 is not expressed on the cell surface of normal T cells or monocytes, but is expressed on mature granulocytes (Le Bien, 1995; Fukukawa, 1986). The antigen is also present on a variety of epithelial types (Turni, 2002). View All» Species Reactivity: Mouse View All» Species Reactivity Note: Demonstrated to react with mouse. View All» Application Notes: Flow Cytometry Analysis: 2 µg from a previous lot detected CD24 in BALB/c splenocytes. View All» Control: Mouse spleen tissue lysate View All» Quality Assurance: Evaluated by Western Blot in mouse spleen tissue lysate.Western Blot Analysis: 0.5 µg/mL of this antibody detected CD24 on 10 µg of mouse spleen tissue lysate. View All» Purification Method: Protein G Purified View All» Presentation: Purified rat monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: P24807 View All» Entrez Gene Number: NP_033976 View All» Gene Symbol:

• CD24

• CD24A
  View All» Alternate Names:
  • Signal transducer CD24

  • Small cell lung carcinoma cluster 4 antigen

  • CD24 antigen

  • CD24 antigen (small cell lung carcinoma cluster 4 antigen), CD24A
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Western Blotting

    • Flow Cytometry
      View All» UniProt Summary: FUNCTION: May have a specific role to play in early thymocyte development.SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor › GPI-anchor. TISSUE SPECIFICTY: In lymphoid, myeloid, and erythroid cells.PTM: The identity of the N- and O-linked polysaccharides are not reported in Ref.6. The O-linked polysaccharides on Ser-30, Ser-41, Ser-43, and Thr-51 are probably the mucin type linked to GalNAc.SEQUENCE SIMILARITIES: Belongs to the CD24 family. View All» Product Name: Anti-CD24, clone M1/69 View All» Concentration: 1.0 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Rat View All»
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