Merck Millipore代理MABF75 Anti-IL-2Ra (CD25), clone PC 61 5.3

2025-06-27

货号:MABF75

品牌:Merck Millipore

规格:EA

目录价:¥3108.00

市场价格:¥2641.80

会员价格:¥2486.40

金山科研平台,产品价格货期咨询微信:jinshanbio Description: Anti-IL-2Ra (CD25) Antibody, clone PC 61 5.3 | MABF75 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: 31 kDa calculated View All» Immunogen: B6.1 mouse cytotoxic T-cell line View All» Clone: PC 61 5.3 View All» Isotype: IgG1κ View All» Background Information: Interleukin-2 receptor subunit alpha (IL-2Rα or CD25) is a single-pass type I membrane protein containing 2 Sushi (CCP/SCR) domains and is one of three chains comprising IL-2R complex. IL-2Rα is a critical component of this complex as it is necessary for determining IL-2 binding. It is also an important factor in the development and proliferation of T cells. Studies have shown IL-2Rα to be down-regulated in cancer patients, suggesting an important role for IL-2Rα in the function of tumor-reactive cytotoxic lymphocytes. View All» Species Reactivity: Mouse View All» Species Reactivity Note: Demonstrated to react with mouse. View All» Control: Balb/c splenocytes View All» Quality Assurance: Evaluated by Flow Cytometry in Balb/c splenocytes.Flow Cytometry Analysis: A 1:400 dilution of this antibody detected IL-2Rα (CD25) in Balb/c splenocytes. View All» Purification Method: Protein G Purified View All» Presentation: Purified rat monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: P01590 View All» Entrez Gene Number: NP_032393 View All» Gene Symbol:

  • IL2RA

  • IL2R

  • p55

  • CD25

  • IDDM10

  • IL-2-RA

  • TCGFR

    View All» Alternate Names:
    • interleukin 2 receptor, alpha

    • TAC antigen

    • interleukin-2 receptor subunit alpha

    • IL-2 receptor subunit alpha

    • CD25 antigen

    • IL-2R subunit alpha

      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Flow Cytometry View All» UniProt Summary: FUNCTION: Receptor for interleukin-2.SUBUNIT STRUCTURE: Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. SEQUENCE SIMILARITIES: Contains 2 Sushi (CCP/SCR) domains. View All» Product Name: Anti-IL-2Ra (CD25), clone PC 61 5.3 View All» Concentration: 1 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 50 μg View All» Format: Purified View All» Host: Rat View All»

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