货号：MABN270

品牌：Merck Millipore

规格：

目录价：￥4439.00

市场价格：￥3773.15

会员价格：￥3551.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-alpha-dystrobrevin Antibody, clone 1D11.1 | MABN270 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~83 kDa observed. Uniprot describes 10 isoforms ranging from ~22 kDa to ~84 kDa. View All» Immunogen: GST-tagged recombinant protein corresponding to human alpha-dystrobrevin. View All» Clone: 1D11.1 View All» Isotype: IgG1κ View All» Background Information: Alpha-dystrobrevin belongs to the dystrophin family and is a cytoplasmic component of the dystrophin-associated protein complex. The complex localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Defects in Alpha-dystrobrevin arrests myocardial morphogenesis leading to left ventricular non-compaction type 1. This disorder is characterized by a hypertrophic left ventricle with deep trabeculations and with poor systolic function, with or without associated left ventricular dilation. In some cases, it is associated with other congenital heart anomalies such as ventricular septal defects, pulmonic stenosis and atrial septal defects. The right ventricle may also be affected. View All» Species Reactivity:

• Human

• Mouse
  View All» Application Notes: Western Blot Analysis: 0.25 µg/mL from a representative lot detected alpha-dystrobrevin in 10 µg of mouse leg muscle tissue lysate.Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected alpha-dystrobrevin in human cerebellum and human skeletal muscle tissues. View All» Control: Human skeletal muscle tissue lysate View All» Quality Assurance: Evaluated by Western Blot in human skeletal muscle tissue lysate.Western Blot Analysis: 0.5 µg/mL of this antibody detected alpha-dystrobrevin in 10 µg of human skeletal muscle tissue lysate. View All» Purification Method: Protein G purified View All» Presentation: Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q9Y4J8 View All» Entrez Gene Number: NP_001121647 View All» Gene Symbol:
  • DTNA

  • DRP3
    View All» Alternate Names:
    • Dystrobrevin alpha

    • DTN-A

    • Alpha-dystrobrevin

    • Dystrophin-related protein 3
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Immunohistochemistry
        View All» Product Name: Anti-alpha-dystrobrevin, clone 1D11.1 View All» Concentration: 0.5 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Mouse View All»
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