货号：MABN89

品牌：Merck Millipore

规格：

目录价：￥4264.00

市场价格：￥3624.40

会员价格：￥3411.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-PCTAIRE-1 kinase Antibody, clone 9G10.1 | MABN89 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~60 kDa observed. The calculated molecular weight of this protein is 56 kDa, but can be observed at ~60-65 kDa due to high glycosylation. Uncharacterized bands at ~20 kDa and ~17 kDa may be observed in some lysates. View All» Immunogen: GST-tagged recombinant protein corresponding to human PCTAIRE-1 kinase. View All» Clone: 9G10.1 View All» Isotype: IgMλ View All» Background Information: PCTAIRE-1 kinase is a member of the cyclin-dependent kinase (cdk) family, found in terminally differentiated cells in brain, testis, and in many immortalised and transformed cell lines. PCTAIRE 1 kinase displays peak activity in G2 and S phase. Recently, studies have shown that PCTAIRE-1 kinase is phosphorylated and regulated by Cdk5/p35. View All» Species Reactivity:

• Human

• Rat

• Mouse
  View All» Species Reactivity Note: Demonstrated to react with Human, Rat, and Mouse. View All» Application Notes: Western Blot Analysis: A 1:5,000 dilution from a representative lot detected PCTAIRE-1 kinase on 10 µg of human testis tissue lysate.Immunohistochemistry Analysis: A 1:100 dilution from a representative lot detected PCTAIRE-1 kinase in human prostate tissue. View All» Control: Rat testis tissue lysate View All» Quality Assurance: Evaluated by Western Blot in rat testis tissue lysate.Western Blot Analysis: A 1:1,000 dilution of this antibody detected PCTAIRE-1 kinase on 10 µg of rat testis tissue lysate. View All» Purification Method: Purified by ion exchange chromatography View All» Presentation: Purified mouse monoclonal IgMλ in buffer containing PBS with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q00536 View All» Entrez Gene Number: NP_001163931 View All» Gene Symbol:
  • CDK16

  • PCTK1
    View All» Alternate Names:
    • Cyclin-dependent kinase 16

    • Cell division protein kinase 16

    • PCTAIRE-motif protein kinase 1

    • Serine/threonine-protein kinase PCTAIRE-1
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Immunohistochemistry
        View All» Entrez Gene Summary: The protein encoded by this gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It may play a role in signal transduction cascades in terminally differentiated cells; in exocytosis; and in transport of secretory cargo from the endoplasmic reticulum. This gene is thought to escape X inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2009]. View All» UniProt Summary: FUNCTION: May play a role in signal transduction cascades in terminally differentiated cells.CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.SUBUNIT STRUCTURE: Found in a complex containing CABLES1, CDK17 and TDRD7. Interacts with YWHAH, YWHAQ and YWHAZ (By similarity).SEQUENCE SIMILARITIES: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.Contains 1 protein kinase domain. View All» Product Name: Anti-PCTAIRE-1 kinase, clone 9G10.1 View All» Concentration: 0.25 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Purified View All» Host: Mouse View All»
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