货号：MABS13

品牌：Merck Millipore

规格：EA

目录价：￥3108.00

市场价格：￥2641.80

会员价格：￥2486.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-G protein-coupled receptor kinase 7 Antibody, clone 10A9.1 | MABS13 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~ 62 kDa observed View All» Epitope: 0 View All» Immunogen: Histidine-tagged recombinant protein corresponding to human G protein-coupled receptor kinase 7. View All» Clone: 10A9.1 View All» Isotype: IgG2aκ View All» Background Information: G protein-coupled receptor kinase 7 (GRK7) is a distinct visual kinase pigment found in retinal cones and is a recently identified member of the AGC Ser/Thr protein kinase family. GRK7 actively phosphorylates rhodopsins, signaling their deactivation. Studies have shown the specific activity of GRK7 to be roughly 10 times higher than its rod counterpart GRK1. It is also much more highly expressed. GRK7 has been reported in several vertebrate species including human, monkey, pig, and 13-lined ground squirrel; however, it is entirely absent from the mouse genome. View All» Species Reactivity:

• Rabbit

• Human
  View All» Species Reactivity Note: Demonstrated to react with human and rabbit. View All» Application Notes: Immunohistochemistry Analysis: 1:300 dilution from a previous lot detected G protein-coupled receptor kinase 7 in rabbit eye tissue. View All» Control: Rabbit retina tissue lysate View All» Quality Assurance: Evaluated by Western Blot in rabbit retina tissue lysate.Western Blot Analysis: 0.5 µg/mL of this antibody detected G protein-coupled receptor kinase 7 on 10 µg of rabbit retina tissue lysate. View All» Purification Method: Protein G View All» Presentation: Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q8WTQ7 View All» Entrez Gene Number: NP_631948 View All» Gene Symbol:
  • GRK7

  • GPRK7
    View All» Alternate Names:
    • G protein-coupled receptor kinase 7

    • G protein-coupled receptor kinase GRK7
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. It is specifically expressed in the retina and the encoded protein has been shown to phosphorylate cone opsins and initiate their deactivation. [provided by RefSeq]. View All» UniProt Summary: FUNCTION: Phosphorylates cone opsins thereby initiating their deactivation.CATALYTIC ACTIVITY: ATP + [G-protein-coupled receptor] = ADP + [G-protein-coupled receptor] phosphate.SUBCELLULAR LOCATION: Membrane; Lipid-anchor. TISSUE SPECIFICTY: Retina. Cones and rod.SEQUENCE SIMILARITIES: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.Contains 1 AGC-kinase C-terminal domain.Contains 1 protein kinase domain.Contains 1 RGS domain. View All» Product Name: Anti-G protein-coupled receptor kinase 7, clone 10A9.1 View All» Concentration: 1 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Mouse View All»
      © 金山科研平台是专业的授权总代理区域代理经销平台。
      © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
      © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
      © 本文地址：https://www.16ao.com/thread-133146.htm
      © Merck Millipore代理MABS13 Anti-GRK7, clone 10A9.1，产品报价联系微信jinshanbio