Merck Millipore代理MABS148 Anti-PKLR, clone 11F12.1

2025-06-28

货号:MABS148

品牌:Merck Millipore

规格:

目录价:¥3574.00

市场价格:¥3037.90

会员价格:¥2859.20

金山科研平台,产品价格货期咨询微信:jinshanbio Description: Anti-PKLR Antibody, clone 11F12.1 | MABS148 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~60 kDa observed View All» Immunogen: GST-tagged recombinant protein corresponding to human PKLR. View All» Clone: 11F12.1 View All» Isotype: IgG2bκ View All» Background Information: PKLR is a pyruvate kinase that catalyzes the transphosphorylation of phosphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). View All» Species Reactivity:

  • Human

  • Mouse

  • Rat

    View All» Species Reactivity Note: Demonstrated to react with Human, Rat, and Mouse. View All» Application Notes: Western Blot Analysis: A 1:1,000 dilution from a representative lot detecte PKLR in 10 µg of rat liver tissue lysate.Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected PKLR in rat liver hepatocytes. View All» Control: HepG2 cell lysate View All» Quality Assurance: Evaluated by Western Blot in HepG2 cell lysate.Western Blot Analysis: A 1:1,000 dilution of this antibody detected PKLR in 10 µg of HepG2 cell lysate. View All» Purification Method: Protein G purified View All» Presentation: Purified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: P30613 View All» Entrez Gene Number: NP_000289 View All» Gene Symbol:
    • PKLR

    • PK1

    • PKL

      View All» Alternate Names:
      • Pyruvate kinase isozymes R/L

      • Pyruvate kinase 1

      • R-type/L-type pyruvate kinase

      • Red cell/liver pyruvate kinase

        View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
        • Western Blotting

        • Immunohistochemistry

          View All» Product Name: Anti-PKLR, clone 11F12.1 View All» Concentration: 0.5 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Purified View All» Host: Mouse View All»

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