货号：MABS190

品牌：Merck Millipore

规格：

目录价：￥4264.00

市场价格：￥3624.40

会员价格：￥3411.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-ROS1 Antibody, clone 20C2.1 | MABS190 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~260 kDa observed View All» Immunogen: GST-tagged recombinant protein corresponding to human ROS1. View All» Clone: 20C2.1 View All» Isotype: IgG2aκ View All» Background Information: Also known as proto-oncogene tyrosine-protein kinase ROS, ROS1 is an orphan receptor tyrosine kinase that belongs to the insulin receptor family. It is highly expressed in the brain, and in primary gliomas. Like other tyrosine kinases, ROS1 phosphorylates a wide range of substrates, including STAT3, VAV3, PTPN11, AKT1, MAPK1, MAPK3, and IRS1, resulting in activation of signaling pathways involved in cell growth, differentiation, proliferation, and survival. View All» Species Reactivity: Rat View All» Species Reactivity Note: Demonstrated to react with Rat. Predicted to react with Human based on immunogen design. View All» Control: PC-12 cell lysate View All» Quality Assurance: Evaluated by Western Blot in PC-12 cell lysate.Western Blot Analysis: 1 µg/mL of this antibody detected ROS1 in 10 µg of PC-12 cell lysate. View All» Purification Method: Protein G purified View All» Presentation: Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: P08922 View All» Entrez Gene Number: NP_002935 View All» Gene Symbol:

• ROS1

• MCF3

• ROS
  View All» Alternate Names:
  • Proto-oncogene tyrosine-protein kinase ROS

  • Proto-oncogene c-Ros

  • Proto-oncogene c-Ros-1

  • Receptor tyrosine kinase c-ros oncogene 1

  • c-Ros receptor tyrosine kinase
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Product Name: Anti-ROS1, clone 20C2.1 View All» Concentration: 1 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Mouse View All»
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