货号：MABT168

品牌：Merck Millipore

规格：

目录价：￥4264.00

市场价格：￥3624.40

会员价格：￥3411.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Delta4 Antibody, clone 16A7.2 | MABT168 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~67 kDa observed. Uniprot gives a calculated molecular weight of 72 kDa. View All» Immunogen: Linear peptide corresponding to human Delta4. View All» Clone: 16A7.2 View All» Isotype: IgMκ View All» Background Information: Delta4, also known as Delta like ligand 4 (DLL4), is a transmembrane protein expressed in the vascular endothelium. Delta4 plays a role in Notch signaling pathway and activates Notch1 and Notch4. Notch signaling pathways play key roles in cell-fate determination and differentiation in many tissues during embryonic and postnatal development. Notch ligands family members are characterized by a DSL domain, EGF repeats, and a transmembrane domain. View All» Species Reactivity: Human View All» Species Reactivity Note: Demonstrated to react with Human. View All» Application Notes: Flow Cytometry Analysis: 0.1 µg from a representative lot detected Delta4 in HEK293 cells. View All» Control: HEK293 cell lysate View All» Quality Assurance: Evaluated by Western Blot in HEK293 cell lysate.Western Blot Analysis: 0.05 µg/mL of this antibody detected Delta4 on 10 µg of HEK293 cell lysate. View All» Purification Method: Purified by ion exchange chromatography View All» Presentation: Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q9NR61 View All» Entrez Gene Number: NP_061947 View All» Gene Symbol: DLL4 View All» Alternate Names:

• Delta-like protein 4

• Drosophila Delta homolog 4

• Delta4
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • Western Blotting

  • Flow Cytometry
    View All» Entrez Gene Summary: This gene is a homolog of the Drosophila delta gene. The delta gene family encodes Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. [provided by RefSeq, Jul 2008]. View All» UniProt Summary: FUNCTION: Plays a role in the Notch signaling pathway. Activates Notch-1 and Notch-4 (By similarity).SUBUNIT STRUCTURE: Binds to Notch-1 and Notch-4 (By similarity).SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein Probable. TISSUE SPECIFICITY: Expressed in vascular endothelium.DOMAIN: The Delta-Serrate-Lag2 (DSL) domain is required for binding to the Notch receptor.PTM: Ubiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation (By similarity).SEQUENCE SIMILARITIES: Contains 1 DSL domain.Contains 8 EGF-like domains. View All» Product Name: Anti-Delta4, clone 16A7.2 View All» Concentration: 0.5 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Mouse View All»
    © 金山科研平台是专业的授权总代理区域代理经销平台。
    © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
    © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
    © 本文地址：https://www.16ao.com/thread-133242.htm
    © Merck Millipore代理MABT168 Anti-Delta4, clone 16A7.2，产品报价联系微信jinshanbio