货号：MABT171

品牌：Merck Millipore

规格：200UL

目录价：￥5513.00

市场价格：￥4686.05

会员价格：￥4410.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-MMP-9 (Active) Antibody, clone 4A3 | MABT171 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes the N-terminus of MMP-9 (Active). View All» Molecular Weight: ~67 kDa observed. Under reducing conditions in SDS-PAGE, MMP-9 monomer (proenzyme) is observed as a major band at ~ 92 kDa. Activation of MMP-9 proenzyme with trypsin yields different active forms at ~64, ~67, and ~82 kDa in a time dependent manner (Duncan, M. E., et al. 1998. Eur J Biochem. 258(1):37-43). View All» Epitope: N-terminus View All» Immunogen: Ovalbumin-conjugated linear peptide corresponding to the N-terminus of human MMP-9 (Active). View All» Clone: 4A3 View All» Isotype: IgG1κ View All» Background Information: Matrix metalloproteinase 9 (MMP-9), a member of the peptidase M10A family, is a multidomain zinc metalloproteinase enzyme, which is highly expressed in neurons and glia of the hippocampus, cerebral cortex, and cerebellum. The active MMP-9 is formed upon cell stimulation by enzymatic cleavage of the precursor, proMMP-9. Because of its function in tissue degradation, MMP-9 is tightly regulated by multiple mechanisms, including glycosylation, inhibition by TIMP1, internalization, and sequestration. MMP-9 plays an important role in long-term potentiation, synaptic plasticity, and memory. Several studies have reported an increase in levels of MMP-9 after CNS injury, as well during the development of various cancers. View All» Species Reactivity: Human View All» Application Notes: Western Blot Analysis: A representative lot from an independent laboratory detected the active form of MMP-9 in WB (Duncan, M. E., et al. 1998. Eur J Biochem. 258(1):37-43).Immunohistochemistry Analysis: A representative lot from an independent laboratory detected the active form of MMP-9 in oesophageal cancer tissues (Duncan, M. E., et al. 1998. Eur J Biochem. 258(1):37-43). View All» Control: Active form of MMP-9 View All» Quality Assurance: Evaluated by Western Blot with the active form of MMP-9.Western Blot Analysis: A 1:250 dilution from a reprsentative lot detected the active form of MMP-9 in WB. View All» Purification Method: Protein G purified View All» Presentation: Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: P14780 View All» Entrez Gene Number: NP_004985 View All» Gene Symbol:

• MMP9

• CLG4B
  View All» Alternate Names:
  • Matrix metalloproteinase-9

  • MMP-9

  • 92 kDa gelatinase

  • 92 kDa type IV collagenase

  • Gelatinase B

  • GELB
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Western Blotting

    • Immunohistochemistry
      View All» Product Name: Anti-MMP-9 (Active), clone 4A3 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 200 µL View All» Format: Purified View All» Host: Mouse View All»
      © 金山科研平台是专业的授权总代理区域代理经销平台。
      © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
      © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
      © 本文地址：https://www.16ao.com/thread-133243.htm
      © Merck Millipore代理MABT171 Anti-MMP-9 (Active) Antibody, clone 4A3;抗-MMP-9（活性）抗体，克隆4A3store at +2℃ to +8℃，产品报价联系微信jinshanbio