货号：MABT77

品牌：Merck Millipore

规格：100UL

目录价：￥4146.00

市场价格：￥3524.10

会员价格：￥3316.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Thymosin beta-4 Antibody, clone 1H2.1 | MABT77 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~35 kDa observed (GST-tagged recombinant protein, GST-tag is ~28 kDa).Detects the expected 5 kDa protein in endogenous lysates. View All» Immunogen: GST-tagged recombinant protein corresponding to human Thymosin beta-4. View All» Clone: 1H2.1 View All» Isotype: IgG1κ View All» Background Information: Thymosin beta-4 is a small unfolded protein that has a wide range of functions such as regulating angiogenesis, inflammation, wound healing and development. Thymosin beta-4 is thought to be important in regulating conformation and structural dynamics of actin monomers. It has also been implicated in promoting rapid corneal wound healing and diminishing inflammation after alkali injury. Thymosin beta-4 has been found in very high numbers in malignant tumors and the local release of Thymosin beta-4 may play a role in tumor behavior. Recent research has also implicated Thymosin beta-4 in purinergic signaling, increasing cell surface ATP levels. View All» Species Reactivity:

• Recombinant Human Protein

• Human
  View All» Species Reactivity Note: Demonstrated to react with Human. View All» Application Notes: Western Blot Analysis: A 1:500 dilution from a representative lot detected Thymosin beta-4 in 10 µg of HL-60 cell lysate. Immunohistochemistry Analysis: A 1:150 dilution from a representative lot detected Thymosin beta-4 in normal human tonsil tissue. View All» Control: Thymosin beta-4 recombinant protein (GST-tagged) View All» Quality Assurance: Evaluated by Western Blot in Thymosin beta-4 recombinant protein.Western Blot Analysis: A 1:1,000 dilution of this antibody detected 10 µg of Thymosin beta-4 recombinant protein (GST-tagged). View All» Purification Method: Protein G Purified View All» Presentation: Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: P62328 View All» Entrez Gene Number: NP_066932 View All» Gene Symbol:
  • TMSB4X

  • TB4X

  • THYB4

  • TMSB4
    View All» Alternate Names:
    • Thymosin beta-4

    • T beta-4

    • Fx

    • Hematopoietic system regulatory peptide

    • Seraspenide
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Immunohistochemistry
        View All» Entrez Gene Summary: This gene encodes an actin sequestering protein which plays a role in regulation of actin polymerization. The protein is also involved in cell proliferation, migration, and differentiation. This gene escapes X inactivation and has a homolog on chromosome Y. [provided by RefSeq]. View All» UniProt Summary: FUNCTION: Plays an important role in the organization of the cytoskeleton (By similarity). Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.Seraspenide inhibits the entry of hematopoeitic pluripotent stem cells into the S-phase (By similarity).SUBCELLULAR LOCATION: Cytoplasm › cytoskeleton. TISSUE SPECIFICTY: Expressed in several hemopoietic cell lines and lymphoid malignant cells. Decreased levels in myeloma cells. INDUCTION: By alpha interferons. Decreased levels in THP-1 cells after treatment with recombinant interferon-lambda.SEQUENCE SIMILARITIES: Belongs to the thymosin beta family. View All» Product Name: Anti-Thymosin beta-4, clone 1H2.1 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Purified View All» Host: Mouse View All»
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        © Merck Millipore代理MABT77 Anti-Thymosin beta-4, clone 1H2.1;store at +2℃ to +8℃，产品报价联系微信jinshanbio