Merck Millipore代理05-385 Anti-Talin (human) Antibody, clone TA205;抗-Talin(人)抗体,克隆TA205store at -20℃

2025-06-27

货号:05-385

品牌:Merck Millipore

规格:200Ug

目录价:¥4497.00

市场价格:¥3822.45

会员价格:¥3597.60

金山科研平台,产品价格货期咨询微信:jinshanbio Description: Anti-Talin (human) Antibody, clone TA205 | 05-385 View All» Replaces: CBL227 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: Talin View All» Molecular Weight: 200kDa View All» Immunogen: Human Talin View All» Isotype: IgG1 View All» Species Reactivity:

  • Human

  • Mouse

  • Rabbit

    View All» Quality Assurance: routinely evaluated by immunoblot on a human A431 RIPA cell lysate View All» Purification Method: Protein A chromatography View All» Presentation: PBS, pH 7.4, 0.05% sodium azide View All» Storage Conditions: 2 years at -20°C View All» UniProt Number: Q9Y490 View All» Entrez Gene Number: NM_006289 View All» Gene Symbol:
    • TLN1

    • KIAA1027

    • Talin-1.

    • ILWEQ

    • TLN

    • talin

      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Immunoprecipitation

      • Western Blotting

      • Immunohistochemistry

        View All» Entrez Gene Summary: This gene encodes a cytoskeletal protein which is concentrated in areas of cell-substratum and cell-cell contacts. This protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin. View All» UniProt Summary: FUNCTION: SwissProt: Q9Y490 # Probably involved in connections of major cytoskeletal structures to the plasma membrane. High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts (By similarity).SIZE: 2541 amino acids; 269767 Da SUBUNIT: Binds with high affinity to vinculin and with low affinity to integrins. Interacts with PIP5K1C and NRAP. Interacts with LAYN.SUBCELLULAR LOCATION: Cell projection, ruffle membrane (By similarity). Note=Colocalizes with LAYN at the membrane ruffles (By similarity).SIMILARITY: SwissProt: Q9Y490 ## Contains 1 FERM domain. & Contains 1 I/LWEQ domain. View All» Brand Family: Upstate View All» Product Name: Anti-Talin (human) Antibody, clone TA205 | 05-385 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 200 µg View All» Format: Purified View All» Host: Mouse View All»

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