货号：05-430

品牌：Merck Millipore

规格：EA

目录价：￥3550.00

市场价格：￥3017.50

会员价格：￥2840.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-INK4b (p15) Antibody | 05-430 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: p15 View All» Molecular Weight: 15 kDa View All» Immunogen: Full length fusion protein correspond-ing to human p15 sequence View All» Isotype: IgG1 View All» Species Reactivity:

• Human

• Mouse
  View All» Quality Assurance: Routinely evaluated by immunoblot on RIPA lysates from HeLa cells View All» Presentation: culture supernatant with 0.05% sodium azide View All» Storage Conditions: 2 years at -20°C View All» UniProt Number: P42772 View All» Entrez Gene Number: NM_004936 View All» Gene Symbol:
  • CDKN2B

  • TP15

  • p15INK4b

  • p14-INK4b

  • MTS2

  • p15-INK4b

  • p14_INK4B

  • p15INK4B

  • INK4B

  • P15

  • CDK4I

  • p15_INK4B
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunoprecipitation

    • Western Blotting
      View All» Entrez Gene Summary: This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. View All» UniProt Summary: FUNCTION: SwissProt: P42772 # Interacts strongly with CDK4 and CDK6. Potent inhibitor. Potential effector of TGF-beta induced cell cycle arrest.SIZE: 138 amino acids; 14722 Da SUBUNIT: Heterodimer of CDKN2B with CDK4 or CDK6.DISEASE:SwissProt: P42772 # Defects in CDKN2B are involved in tumor formation.SIMILARITY: SwissProt: P42772 ## Belongs to the CDKN2 cyclin-dependent kinase inhibitor family. & Contains 4 ANK repeats. View All» Brand Family: Upstate View All» Product Name: Anti-INK4b (p15) Antibody | 05-430 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 400 µL View All» Format: Purified View All» Host: Mouse View All»
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